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2012-2022 年中国中南部欠发达省份产妇发生接近死亡病例的风险因素。

Risk factors for maternal near-miss in an undeveloped province in south-central China, 2012-2022.

机构信息

Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China.

出版信息

BMC Public Health. 2024 Jun 6;24(1):1526. doi: 10.1186/s12889-024-18970-4.

Abstract

OBJECTIVE

To explore the risk factors for maternal near-miss (MNM) using the WHO near-miss approach.

METHODS

Data were obtained from the Maternal Near-Miss Surveillance System in Hunan Province, China, 2012-2022. Multivariate logistic regression analysis (method: Forward, Wald, α = 0.05) and adjusted odds ratios (aORs) were used to identify risk factors for MNM.

RESULTS

Our study included 780,359 women with 731,185 live births, a total of 2461 (0.32%) MNMs, 777,846 (99.68%) non-MNMs, and 52 (0.006%) maternal deaths were identified. The MNM ratio was 3.37‰ (95%CI: 3.23-3.50). Coagulation/hematological dysfunction was the most common cause of MNM (75.66%). Results of multivariate logistic regression analysis showed risk factors for MNM: maternal age > = 30 years old (aOR > 1, P < 0.05), unmarried women (aOR = 2.21, 95%CI: 1.71-2.85), number of pregnancies > = 2 (aOR > 1, P < 0.05), nulliparity (aOR = 1.51, 95%CI: 1.32-1.72) or parity > = 3 (aOR = 1.95, 95%CI: 1.50-2.55), prenatal examinations < 5 times (aOR = 1.13, 95%CI: 1.01-1.27), and number of cesarean sections was 1 (aOR = 1.83, 95%CI: 1.64-2.04) or > = 2 (aOR = 2.48, 95%CI: 1.99-3.09).

CONCLUSION

The MNM ratio was relatively low in Hunan Province. Advanced maternal age, unmarried status, a high number of pregnancies, nulliparity or high parity, a low number of prenatal examinations, and cesarean sections were risk factors for MNM. Our study is essential for improving the quality of maternal health care and preventing MNM.

摘要

目的

使用世界卫生组织(WHO)的接近错失(near-miss)方法探讨产妇接近错失(MNM)的危险因素。

方法

数据来自中国湖南省的产妇接近错失监测系统,时间为 2012 年至 2022 年。采用多变量逻辑回归分析(方法:向前、沃尔德、α=0.05)和调整后的优势比(aOR)来识别 MNM 的危险因素。

结果

本研究纳入了 780359 名女性和 731185 例活产,共发现 2461 例(0.32%)MNM、777846 例(99.68%)非 MNM 和 52 例(0.006%)产妇死亡。MNM 发生率为 3.37‰(95%CI:3.23-3.50)。凝血/血液功能障碍是 MNM 最常见的原因(75.66%)。多变量逻辑回归分析结果显示 MNM 的危险因素包括:年龄≥30 岁(aOR>1,P<0.05)、未婚(aOR=2.21,95%CI:1.71-2.85)、妊娠次数≥2 次(aOR>1,P<0.05)、初产妇(aOR=1.51,95%CI:1.32-1.72)或多产妇(aOR=1.95,95%CI:1.50-2.55)、产前检查次数<5 次(aOR=1.13,95%CI:1.01-1.27)和剖宫产次数为 1 次(aOR=1.83,95%CI:1.64-2.04)或≥2 次(aOR=2.48,95%CI:1.99-3.09)。

结论

湖南省 MNM 发生率相对较低。高龄、未婚、多次妊娠、初产妇或多产妇、产前检查次数少、剖宫产次数是 MNM 的危险因素。本研究对于提高孕产妇保健质量和预防 MNM 具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b6b/11157777/ebdd9e20d788/12889_2024_18970_Figa_HTML.jpg

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