Ryu Sukhyun, Kim Bryan Inho, Chun Byung Chul
Division of Infectious Disease Control, Gyeonggi Provincial Government, 1 Hyowon-ro, Paldal-gu, Suwon, 16444, Republic of Korea; Department of Epidemiology and Health Informatics, Graduate School of Public Health, Korea University, 73 Inchon-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Department of Epidemiology and Health Informatics, Graduate School of Public Health, Korea University, 73 Inchon-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
J Infect Chemother. 2018 Sep;24(9):689-694. doi: 10.1016/j.jiac.2018.06.010. Epub 2018 Jul 11.
An outbreak of respiratory tract infection due to Respiratory Syncytial Virus (RSV) type B in a postpartum center was reported on February 1, 2017. Investigation was conducted to identify the magnitude, possible source of infection and risk factors for this outbreak on February 2, 2017.
A retrospective cohort study was conducted. A case was defined as a neonate having respiratory symptoms with or without fever and stayed at the postpartum center between January 1, 2017 and February 3, 2017. Daily records of neonates were reviewed, and all parents who stayed at the postpartum center were interviewed. Virological testing of real-time polymerase chain reaction was conducted for the neonates having respiratory illness, the parents and all staff members in the facility.
This outbreak occurred between January 17, 2017 and February 7, 2017 in a postpartum center. Thirty-five (58.3%) neonates among 59 neonates were identified as cases and 12 neonates were confirmed to be RSV-B positive. The longer length of stay in the postpartum center is the only risk factor (Relative Risk = 8.10, 95% Confidence Interval:1.84-35.62, p < 0.01) in this outbreak. Two nursing staffs and eight parents were confirmed as RSV-B positive.
Longer periods of stay in the postpartum center had an increased chance of becoming infected with RSV during this outbreak. Isolation of cases and temporary closure with environmental cleaning were recommended to the postpartum center.
2017年2月1日报告了一家产后护理中心发生的由B型呼吸道合胞病毒（RSV）引起的呼吸道感染暴发事件。2017年2月2日开展了调查，以确定此次暴发的规模、可能的感染源和危险因素。
进行了一项回顾性队列研究。病例定义为2017年1月1日至2017年2月3日期间在产后护理中心出现有或无发热的呼吸道症状的新生儿。查阅了新生儿的每日记录，并对所有住在产后护理中心的家长进行了访谈。对患有呼吸道疾病的新生儿、家长以及该机构的所有工作人员进行了实时聚合酶链反应的病毒学检测。
此次暴发于2017年1月17日至2017年2月7日在一家产后护理中心发生。59名新生儿中有35名（58.3%）被确定为病例，12名新生儿被确诊为RSV-B阳性。在此次暴发中，在产后护理中心停留时间较长是唯一的危险因素（相对危险度=8.10，95%置信区间：1.84-35.62，p<0.01）。两名护理人员和八名家长被确诊为RSV-B阳性。
在此次暴发期间，在产后护理中心停留时间较长会增加感染RSV的机会。建议产后护理中心对病例进行隔离并进行环境清洁后临时关闭。
