Hellgren E C, Lochmiller R L, Amoss M S, Grant W E
J Wildl Dis. 1985 Oct;21(4):417-25. doi: 10.7589/0090-3558-21.4.417.
Serial physiological responses were examined for 150 min from captive collared peccaries during immobilization with ketamine hydrochloride. Rectal temperatures decreased significantly (P less than 0.01) during anesthesia. Serum concentrations of total proteins, albumin, cholesterol, alanine aminotransferase, and calcium declined significantly (P less than 0.05) during the first 45 min post-immobilization before stabilizing. Concentrations of lactate dehydrogenase and alkaline phosphatase in sera showed similar but nonsignificant (P greater than 0.05) trends. Inorganic phosphorus and aspartate aminotransferase concentrations increased significantly (P less than 0.05) throughout the trial. Concentrations of serum glucose and glucocorticoid during the immobilization period were highly variable between individuals. Serum electrolytes, urea nitrogen, creatinine, gammaglutamyl transferase and progesterone were not significantly (P greater than 0.05) affected by immobilization. Elevations in serum testosterone were noted. Results indicated appropriate sampling times relative to immobilization for assay of particular serum biochemicals and steroid hormones during investigations of the physiology of the collared peccary.
在用盐酸氯胺酮使圈养的领西貒麻醉固定的150分钟内，对其一系列生理反应进行了检测。麻醉期间直肠温度显著下降（P<0.01）。固定后最初45分钟内，血清总蛋白、白蛋白、胆固醇、丙氨酸转氨酶和钙的浓度显著下降（P<0.05），之后趋于稳定。血清中乳酸脱氢酶和碱性磷酸酶的浓度呈现相似但不显著（P>0.05）的变化趋势。在整个试验过程中，无机磷和天冬氨酸转氨酶的浓度显著升高（P<0.05）。麻醉期间个体间血清葡萄糖和糖皮质激素的浓度变化很大。血清电解质、尿素氮、肌酐、γ-谷氨酰转移酶和孕酮未受到麻醉固定的显著（P>0.05）影响。血清睾酮升高。结果表明，在对领西貒生理学进行研究时，相对于麻醉固定，针对特定血清生化物质和类固醇激素检测有合适的采样时间。
