Russell J, Bass P
Am J Physiol. 1985 Dec;249(6 Pt 1):G662-7. doi: 10.1152/ajpgi.1985.249.6.G662.
Dietary fibers such as psyllium and guar gum have been shown to delay the gastric emptying of liquids and solids, presumably due to an increase in meal viscosity. For liquid test meals containing fats, delayed gastric emptying is associated with a reversal of the usual antral-to-duodenal contractile gradient. The present studies were performed to determine whether the gastric emptying of increasingly viscous psyllium and guar gum meals was associated with antroduodenal motility changes. Dogs were surgically fitted with mid-duodenal cannulas for the measurement of gastric emptying. Strain-gauge force transducers were used to monitor antral and duodenal contractile responses to the test meals. Low-viscosity fiber meals emptied from the stomach rapidly (E 1/2 approximately 10 min) compared with the high-viscosity meals (E 1/2 approximately 40 min). None of the test meals stimulated antral or duodenal motility despite differences in gastric emptying time. Other motor parameters such as the time of reappearance and the duration of the burst interval were also unchanged. We conclude a) as test meals' fiber content and viscosity increase, gastric emptying is slowed; and b) viscosity-related delays in gastric emptying are not due to an effect on postprandial antroduodenal motility.
诸如车前草和瓜尔豆胶之类的膳食纤维已被证明会延缓液体和固体食物的胃排空，这可能是由于食物粘度增加所致。对于含有脂肪的液体测试餐，胃排空延迟与通常的胃窦至十二指肠收缩梯度的逆转有关。进行本研究以确定粘性不断增加的车前草和瓜尔豆胶餐的胃排空是否与胃十二指肠运动变化有关。给狗进行手术，在十二指肠中部植入套管以测量胃排空。使用应变片力传感器监测胃窦和十二指肠对测试餐的收缩反应。与高粘度餐（排空半衰期约40分钟）相比，低粘度纤维餐从胃中排空得更快（排空半衰期约10分钟）。尽管胃排空时间不同，但没有一种测试餐刺激胃窦或十二指肠运动。其他运动参数，如再次出现的时间和爆发间隔的持续时间也没有变化。我们得出结论：a）随着测试餐的纤维含量和粘度增加，胃排空减慢；b）与粘度相关的胃排空延迟不是由于对餐后胃十二指肠运动的影响。
