人类液体餐胃排空期间的 antropyloroduodenal 活动。（注：“antropyloroduodenal”这个词可能有误，正常医学术语中类似的应该是“antropyloroduodenal” 中“antro-”可能有误，推测正确的可能是“gastro-”即“胃幽门十二指肠的” ，整体准确意思可能是“人类液体餐胃排空期间的胃幽门十二指肠活动” ）

Antropyloroduodenal activity during gastric emptying of liquid meals in humans.

作者信息

Dooley C P, Valenzuela J E

机构信息

Department of Medicine, Los Angeles County-University of Southern California Medical Center 90033.

出版信息

Am J Physiol. 1988 Jul;255(1 Pt 1):G93-8. doi: 10.1152/ajpgi.1988.255.1.G93.

DOI:10.1152/ajpgi.1988.255.1.G93

PMID:3389417

Abstract

The present study examines the possible roles of the pylorus and the proximal duodenum in the gastric emptying of two liquid meals in six healthy volunteers. Gastric emptying of a saline meal (150 mM) and an acid meal (120 mM hydrochloric acid) were measured by the double-sampling dye dilution technique while antroduodenal motility was monitored with a continuously perfused catheter system. Pyloric region pressures were measured with a Dent sleeve. The acid meal (t1/2 = 13.5 +/- 1.8 min) emptied significantly (P less than 0.01) slower than the saline meal (t1/2 = 3.5 +/- 0.7 min). This slowing in the emptying of the acid meal was associated with significant (P less than 0.05) increments in tonic pyloric activity and phasic contractions of the proximal duodenum. Thus the gastric emptying of liquid meals is a complex process involving all components of the gastroduodenal region.

摘要

本研究检测了幽门和十二指肠近端在6名健康志愿者胃排空两种流食过程中可能发挥的作用。采用双样本染料稀释技术测定盐水餐（150 mM）和酸餐（120 mM盐酸）的胃排空情况，同时使用连续灌注导管系统监测胃十二指肠运动。用登特套管测量幽门区域压力。酸餐（t1/2 = 13.5 +/- 1.8分钟）的排空速度明显（P < 0.01）慢于盐水餐（t1/2 = 3.5 +/- 0.7分钟）。酸餐排空减慢与幽门紧张性活动和十二指肠近端的相性收缩显著增加（P < 0.05）有关。因此，流食的胃排空是一个涉及胃十二指肠区域所有组成部分的复杂过程。