Pedemonte Oneglio, Vera Andres, Merello Lorenzo, Novajas Manuel, Aranda Fernando, Ibarra Julio, Muñoz Jose A, Alburquerque Javier, Espinoza Paulina, Cárdenas Felipe, Aránguiz-Santander Ernesto
Department of Cardiovascular Surgery, Hospital Gustavo Fricke, Viña del Mar, Chile.
Department of Cardiovascular Diseases, Universidad de Valparaíso, Valparaíso, Chile.
J Thorac Dis. 2018 Jun;10(Suppl 15):S1751-S1757. doi: 10.21037/jtd.2018.02.83.
The need to have a variety of tools to deal with end-stage heart failure (ES-HF), along with the limited heart transplantation availability encouraged us to create a pilot Left ventricular assist device (LVAD) program in a public health care system hospital in Chile.
A retrospective analysis of the first nine patients of an ongoing LVAD program initiated on August 2013 was performed, completing an average of 30 months of follow-up. The most important events regarding to morbidity and mortality are described.
Nine patients with ES-HF underwent LVAD implantation surgery; one of them died 23 days after surgery and another died after 11 months. One patient successfully underwent heart transplantation after 16 months of HeartWare ventricular assist device (HVAD) support; the other six patients remain in the program and have an average follow-up of 846 days at the time of this study (range, 23-1,481 days). The survival rate at 6, 12 and 18 months follow-up was 89%, 78% and 78% respectively.
This new pioneering LVAD program in Chile has been successful and now constitutes a vital adjunct to all who work in heart transplantation and ES-HF programs. It offers an effective therapeutic alternative when there is a severe donor shortage, in cases of atypical blood types, emergencies, exceptional cases with contraindication for heart transplantation or when there is important donor-receiver size mismatch.
由于需要有多种工具来应对终末期心力衰竭(ES-HF),同时心脏移植的可及性有限,这促使我们在智利的一家公共卫生保健系统医院开展了一项左心室辅助装置(LVAD)试点项目。
对2013年8月启动的一个正在进行的LVAD项目的前9名患者进行回顾性分析,平均随访30个月。描述了与发病率和死亡率相关的最重要事件。
9例ES-HF患者接受了LVAD植入手术;其中1例术后23天死亡,另1例在11个月后死亡。1例患者在接受HeartWare心室辅助装置(HVAD)支持16个月后成功接受了心脏移植;其他6例患者仍在该项目中,在本研究时平均随访846天(范围为23 - 1481天)。随访6个月、12个月和18个月时的生存率分别为89%、78%和78%。
智利这个新的开创性LVAD项目取得了成功,现在已成为所有从事心脏移植和ES-HF项目工作人员的重要辅助手段。当供体严重短缺、血型不典型、紧急情况、心脏移植有禁忌的特殊病例或供受体大小严重不匹配时,它提供了一种有效的治疗选择。