Sato K
Immunology. 1977 Feb;32(2):171-7.
The bone marrow and spleen of normal unimmunized chicks contain lymphoid cells which form rosettes with quail red blood cells (QRBC), but not with sheep red blood cells. The number of these antigen binding cells (QRBC-ABC) were restored to their original level 2-3 weeks after whole body X-irradiation following a temporary but drastic decrease in the number of QRBC-ABC. This recovery is not observed in chicks which have been thymectomized or thymectomized and bursectomized. However, QRBC-ABC numbers were restored in bursectomized chicks comparable with those levels in control chicks. Anti-thymic serum effectively blocked rosette formation and it seems that QRBC-ABC are a thymus-dependent population. Possibly, the thymus exerts an influence on the genesis of QRBC-ABC through a humoral mechanism.
正常未免疫雏鸡的骨髓和脾脏含有淋巴样细胞，这些细胞可与鹌鹑红细胞（QRBC）形成玫瑰花结，但不与绵羊红细胞形成玫瑰花结。这些抗原结合细胞（QRBC-ABC）的数量在全身X线照射后暂时但急剧减少，2至3周后恢复到原来水平。在已进行胸腺切除或胸腺切除并法氏囊切除的雏鸡中未观察到这种恢复。然而，法氏囊切除雏鸡的QRBC-ABC数量恢复到与对照雏鸡相当的水平。抗胸腺血清有效地阻断了玫瑰花结的形成，似乎QRBC-ABC是一个依赖胸腺的细胞群体。胸腺可能通过体液机制对QRBC-ABC的发生产生影响。
