1 Department of Pharmacy, Temple University Hospital , Philadelphia, Pennsylvania.
2 Department of Medicine, Lewis Katz School of Medicine at Temple University , Philadelphia, Pennsylvania.
AIDS Patient Care STDS. 2018 Dec;32(12):490-494. doi: 10.1089/apc.2018.0030. Epub 2018 Jul 23.
Uptake of HIV pre-exposure prophylaxis (PrEP) is low among women at risk for HIV acquisition. Of 468,000 women, whom the United States Centers for Disease Control and Prevention estimates to be eligible for PrEP, only 10,000 unique women have begun therapy through the third quarter of 2015. These data suggest insufficient HIV prevention efforts. This study, conducted at the site of an urban academic medical center with an emergency department HIV prevalence rate of 4%, assesses the knowledge, attitudes, and beliefs of women toward PrEP. A self-administered survey was conducted among women at a family planning obstetrics/gynecology clinic at Temple University Hospital (Philadelphia, PA). Participants assessed their HIV acquisition risk and answered eight questions regarding knowledge, attitudes, and beliefs toward PrEP. Three hundred eighty-nine surveys met inclusion criteria. Sixty-five percent of women were black, and 73% were between 18 and 33 years of age. The median self-perceived risk score was 0 (interquartile range = 2) using a Likert scale. Thirty-three percent of women believed that PrEP could work, and 27% knew that such a regimen existed. Concerns existed toward cost (44%) and side effects (39%). Fifty-seven percent of women surveyed stated that they would take a medication to prevent HIV, and 64% felt comfortable discussing the subject with her doctor. Our data demonstrate a lack of PrEP knowledge, although willingness for uptake among women at risk for HIV acquisition, and a need for directed education and outreach.
在美国疾病控制与预防中心估计有资格接受 PrEP 的 46.8 万名女性中,只有 1 万名独特的女性在 2015 年第三季度开始接受治疗。这些数据表明 HIV 预防工作力度不足。这项在一家拥有急诊部门 HIV 流行率为 4%的城市学术医疗中心进行的研究评估了女性对 PrEP 的知识、态度和信念。在 Temple 大学医院(宾夕法尼亚州费城)的计划生育妇产科诊所对女性进行了一项自我管理的调查。参与者评估了她们感染 HIV 的风险,并回答了关于 PrEP 的知识、态度和信念的八个问题。符合纳入标准的有 389 份调查。65%的女性是黑人,73%的女性年龄在 18 至 33 岁之间。使用李克特量表,中位数自我感知风险评分为 0(四分位距=2)。33%的女性认为 PrEP 可能有效,27%的女性知道有这样的方案。对成本(44%)和副作用(39%)存在担忧。57%的接受调查的女性表示她们会服用预防 HIV 的药物,64%的女性表示她们愿意与医生讨论这个话题。我们的数据表明,尽管存在感染 HIV 风险的女性对 PrEP 的接受意愿,但缺乏 PrEP 知识,需要有针对性的教育和外展。