Korpallová Barbora, Samoš Matej, Bolek Tomáš, Škorňová Ingrid, Kovář František, Kubisz Peter, Staško Ján, Mokáň Marián
1 Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic.
2 Department of Hematology and Blood Transfusion, National Centre of Hemostasis and Thrombosis, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic.
Clin Appl Thromb Hemost. 2018 Nov;24(8):1199-1207. doi: 10.1177/1076029618790092. Epub 2018 Jul 24.
The monitoring of coagulation by viscoelastometric methods-thromboelastography and rotational thromboelastometry-may detect the contributions of cellular and plasma components of hemostasis. These methods might overcome some of the serious limitations of conventional laboratory tests. Viscoelastic testing can be repeatedly performed during and after surgery and thus provides a dynamic picture of the coagulation process during these periods. Several experiences with the use of these methods in cardiovascular surgery have been reported, but there is perspective for more frequent use of these assays in the assessment of platelet response to antiplatelet therapy and in the assessment of coagulation in patients on long-term dabigatran therapy. This article reviews the current role and future perspectives of thromboelastography and thromboelastometry in the management of cardiovascular diseases.
通过黏弹性方法（血栓弹力图和旋转血栓弹力测定法）监测凝血功能，可能会检测到止血过程中细胞成分和血浆成分的作用。这些方法可能会克服传统实验室检测的一些严重局限性。黏弹性检测可在手术期间及术后反复进行，从而提供这些时期凝血过程的动态情况。已有多项关于在心血管手术中使用这些方法的经验报道，但在评估血小板对抗血小板治疗的反应以及评估长期接受达比加群治疗患者的凝血功能方面，这些检测方法还有更频繁使用的前景。本文综述了血栓弹力图和血栓弹力测定法在心血管疾病管理中的当前作用及未来前景。
