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Immunological analysis of the specificity of the autologous humoral response in breast cancer patients.

作者信息

Campbell A M, McCormack M A, Ross C A, Leake R E

出版信息

Br J Cancer. 1986 Jan;53(1):7-11. doi: 10.1038/bjc.1986.2.

DOI:10.1038/bjc.1986.2
PMID:3004548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2001459/
Abstract

The autologous and allogeneic immunological humoral response of breast cancer patients to breast tumours was investigated by ELISA assay of both the serum and the supernatants of transformed lymphocytes from the patients and controls. No specificity or increased titre relative to the controls was observed in serum antibody. However, when the response was dissected by the use of clones of transformed lymphocytes from the patients, considerable specificity could be demonstrated in certain clones while other clones showed a generalised specificity which contributed to the masking of the specific response in the serum. Some of these clones may have clinical potential as diagnostic and prognostic tools.

摘要

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Br J Cancer. 1988 Aug;58(2):182-5. doi: 10.1038/bjc.1988.188.

本文引用的文献

1
Oestrogen-receptor status and endocrine therapy of breast cancer: response rates and status stability.雌激素受体状态与乳腺癌内分泌治疗：缓解率及状态稳定性
Br J Cancer. 1981 Jan;43(1):59-66. doi: 10.1038/bjc.1981.8.
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Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.用人抗原特异性爱泼斯坦-巴尔病毒转化细胞系构建的人杂交瘤。
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Br J Cancer. 1985 Feb;51(2):149-60. doi: 10.1038/bjc.1985.24.
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Breast Cancer Res Treat. 1985;5(2):207-14. doi: 10.1007/BF01805996.
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Relationship of oestrogen-receptor status to survival in breast cancer.
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