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一种用于三维前瞻性血管内成像的具有前端专用集成电路和低电缆数量的二维超声换能器:性能与特性

A 2-D Ultrasound Transducer With Front-End ASIC and Low Cable Count for 3-D Forward-Looking Intravascular Imaging: Performance and Characterization.

作者信息

Janjic Jovana, Tan Mingliang, Daeichin Verya, Noothout Emile, Chen Chao, Chen Zhao, Chang Zu-Yao, Beurskens Robert H S H, van Soest Gijs, van der Steen Antonius F W, Verweij Martin D, Pertijs Michiel A P, de Jong Nico

出版信息

IEEE Trans Ultrason Ferroelectr Freq Control. 2018 Oct;65(10):1832-1844. doi: 10.1109/TUFFC.2018.2859824. Epub 2018 Jul 25.

DOI:10.1109/TUFFC.2018.2859824
PMID:30047876
Abstract

Intravascular ultrasound (IVUS) is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking IVUS (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2-D array transducers, which present major challenges in reducing cable count and device integration. In this work, we present an 80-element lead zirconium titanate matrix ultrasound transducer for FL-IVUS imaging with a front-end application-specific integrated circuit (ASIC) requiring only four cables. After investigating optimal transducer designs, we fabricated the matrix transducer consisting of 16 transmit (TX) and 64 receive (RX) elements arranged on top of an ASIC having an outer diameter of 1.5 mm and a central hole of 0.5 mm for a guidewire. We modeled the transducer using finite-element analysis and compared the simulation results to the values obtained through acoustic measurements. The TX elements showed uniform behavior with a center frequency of 14 MHz, a -3-dB bandwidth of 44%, and a transmit sensitivity of 0.4 kPa/V at 6 mm. The RX elements showed center frequency and bandwidth similar to the TX elements, with an estimated receive sensitivity of /Pa. We successfully acquired a 3-D FL image of three spherical reflectors in water using delay-and-sum beamforming and the coherence factor method. Full synthetic-aperture acquisition can be achieved with frame rates on the order of 100 Hz. The acoustic characterization and the initial imaging results show the potential of the proposed transducer to achieve 3-D FL-IVUS imaging.

摘要

血管内超声(IVUS)是一种用于从人体动脉内腔可视化动脉粥样硬化的成像方式。像慢性完全闭塞这样的复杂病变需要前瞻性血管内超声(FL-IVUS),而不是传统的侧视几何结构。使用二维阵列换能器可以实现容积成像,这在减少电缆数量和设备集成方面带来了重大挑战。在这项工作中,我们展示了一种用于FL-IVUS成像的80元件钛酸锆铅矩阵超声换能器,其前端专用集成电路(ASIC)仅需四根电缆。在研究了最佳换能器设计后,我们制造了由16个发射(TX)和64个接收(RX)元件组成的矩阵换能器,这些元件排列在一个外径为1.5毫米、中心孔为0.5毫米用于导丝的ASIC顶部。我们使用有限元分析对换能器进行建模,并将模拟结果与通过声学测量获得的值进行比较。TX元件表现出均匀的特性,中心频率为14兆赫兹,-3分贝带宽为44%,在6毫米处的发射灵敏度为0.4千帕/伏。RX元件的中心频率和带宽与TX元件相似,并估计接收灵敏度为/帕。我们使用延迟求和波束形成和相干因子方法成功获取了水中三个球形反射器的三维FL图像。全合成孔径采集可以在100赫兹左右的帧率下实现。声学特性和初步成像结果显示了所提出的换能器实现三维FL-IVUS成像的潜力。

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