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采用术前门静脉栓塞支持下的肝脏悬吊技术安全切除侵犯肝脏的肾细胞癌

Safe Resection of Renal Cell Carcinoma with Liver Invasion Using Liver Hanging Technique Supported by Preoperative Portal Vein Embolization.

作者信息

Fujii Masato, Kamimura Toshio, Tsukino Hiromasa, Furukoji Eiji, Sakae Tatefumi, Yano Koichi, Imamura Naoya, Mukai Shoichiro, Nanashima Atsushi, Kamoto Toshiyuki

机构信息

Department of Urology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Department of Radiology, Faculty of medicine, University of Miyazaki, Miyazaki, Japan.

出版信息

Case Rep Urol. 2018 Jun 28;2018:5139034. doi: 10.1155/2018/5139034. eCollection 2018.

Abstract

In cases of RCC with liver involvement, partial hepatectomy is known to provide a better chance of survival for patients. For this reason, complete resection with clear surgical margin is thought to be necessary to achieve favorable outcome. Anterior liver hanging maneuver was extremely useful during hemihepatectomy in this rare type of RCC. A 63-year-old male was diagnosed with a large right renal cell carcinoma. The tumor measured 10 cm in diameter with tumor thrombus toward the inferior vena cava (IVC). In addition, we observed direct infiltration to the liver. We attempted a preoperative portal vein embolization (PVE) to preserve residual liver volume and function after right lobectomy. After PVE the resected volume decreased from 921 cm (71%) to 599 cm (53.4%). During the procedure, a nasogastric tube was placed in the retrohepatic space for liver hanging maneuver according to the original Belghiti's maneuver after dissection of the renal artery and vein. After hepatic parenchymal transection exposing vena cava, the right hepatic veins were safely transected using vascular stapler; right nephrectomy and hemihepatectomy were performed. The patient recovered without postoperative hepatic or urinary complications and has remained free of local recurrence and any de novo metastasis for 18 months.

摘要

在伴有肝脏受累的肾细胞癌(RCC)病例中,已知部分肝切除术能为患者提供更好的生存机会。因此,认为实现切缘清晰的完整切除对于取得良好预后是必要的。在这种罕见类型的RCC进行半肝切除术中,前入路肝脏悬吊术非常有用。一名63岁男性被诊断为巨大右肾细胞癌。肿瘤直径为10厘米,伴有向下腔静脉(IVC)的瘤栓。此外,我们观察到肿瘤直接浸润至肝脏。我们尝试进行术前门静脉栓塞(PVE)以保留右叶切除术后的残余肝体积和功能。PVE后,切除体积从921立方厘米(71%)降至599立方厘米(53.4%)。手术过程中,在肾动静脉解剖后,根据原始的贝尔吉蒂手法,将鼻胃管置于肝后间隙用于肝脏悬吊术。在肝实质离断暴露下腔静脉后,使用血管吻合器安全地离断右肝静脉;进行了右肾切除术和半肝切除术。患者术后恢复良好,无肝脏或泌尿系统并发症,且18个月来无局部复发及任何新发转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15df/6046184/a714682bcc1b/CRIU2018-5139034.001.jpg

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