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经导管主动脉瓣植入术:与单纯镇静相比,使用经食管超声心动图的全身麻醉并不能降低瓣周漏的发生率。

Transcatheter aortic valve implantation: General anesthesia using transesophageal echocardiography does not decrease the incidence of paravalvular leaks compared to sedation alone.

作者信息

Zaouter Cédrick, Smaili Sara, Leroux Lionel, Bonnet Guillaume, Leuillet Sébastien, Ouattara Alexandre

机构信息

Department of Anaesthesia and Intensive Care II, Bordeaux University Hospital, CHU de Bordeaux, 33000 Bordeaux, France.

Department of Cardiology, Bordeaux University Hospital, CHU de Bordeaux, 33000 Bordeaux, France.

出版信息

Ann Card Anaesth. 2018 Jul-Sep;21(3):277-284. doi: 10.4103/aca.ACA_204_17.

Abstract

BACKGROUND

Transcatheter aortic valve implantation (TAVI) is a valid option for patients with severe aortic stenosis judged to be at high surgical risk. For this procedure, there is no agreement on the appropriate type of anesthesia. Sedation offers several advantages, but general anesthesia (GA) leads to less paravalvular leaks (PVLs) probably because of the transesophageal echocardiography (TEE) guidance. The objective was to compare the incidence of PVL among patients receiving conscious sedation (TAVI-S) and patients receiving GA (TAVI-GA). We made the hypothesis that a referral center does not necessitate TAVI-GA to reduce the incidence of moderate-to-severe PVL.

AIM

The primary outcome was the incidence of moderate-to-severe PVL at 30 days after the implantation.

DESIGN AND SETTING

This study design was a retrospective observational trial in a university hospital.

METHODS

The TAVI-S group underwent the procedure under conscious sedation. In the TAVI-GA group, an endotracheal tube and a TEE probe were inserted. After the valve deployment, PVL was assessed by hemodynamic and fluoroscopic measurements in the TAVI-S group. TEE was also used in the TAVI-GA group to evaluate the presence of PVL. When PVL was moderate or severe according to the Valve Academic Research Consortium criteria.

RESULTS

TAVI-S and TAVI-GA were accomplished in 168 (67.5%) and 81 (32.5%) patients, respectively. Our results show no difference between the two groups regarding the incidence and grade of PVL.

CONCLUSION

Performing TAVI under GA with TEE guidance is not associated with a lower incidence of moderate and severe PVL.

摘要

背景

经导管主动脉瓣植入术(TAVI)是判定为手术风险高的严重主动脉瓣狭窄患者的有效选择。对于该手术,合适的麻醉类型尚无共识。镇静有几个优点,但全身麻醉(GA)可能因经食管超声心动图(TEE)引导而导致瓣周漏(PVL)较少。目的是比较接受清醒镇静(TAVI-S)的患者和接受GA(TAVI-GA)的患者中PVL的发生率。我们提出假设,即转诊中心不需要TAVI-GA来降低中重度PVL的发生率。

目的

主要结局是植入后30天中重度PVL的发生率。

设计与地点

本研究设计为在一家大学医院进行的回顾性观察性试验。

方法

TAVI-S组在清醒镇静下进行手术。在TAVI-GA组中,插入气管内导管和TEE探头。瓣膜植入后,TAVI-S组通过血流动力学和荧光透视测量评估PVL。TAVI-GA组也使用TEE评估PVL的存在。当PVL根据瓣膜学术研究联盟标准为中度或重度时。

结果

分别有168例(67.5%)和81例(32.5%)患者完成了TAVI-S和TAVI-GA手术。我们的结果显示,两组在PVL的发生率和分级方面没有差异。

结论

在GA和TEE引导下进行TAVI与中重度PVL的较低发生率无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8545/6078031/2c84cc6d28a0/ACA-21-277-g001.jpg

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