Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Department of Dentistry, Paraiba State University, Campina Grande, Brazil.
Arch Oral Biol. 2018 Nov;95:68-73. doi: 10.1016/j.archoralbio.2018.07.013. Epub 2018 Jul 18.
Palm oil has demonstrated preventive potential against initial erosive demineralization in vitro. This in situ study evaluated the effect of palm oil alone or associated with stannous-containing (Sn) solution on preventing enamel loss from an erosive/abrasive challenge.
This single-blind, randomized, crossover in situ/ex vivo study was developed in four phases (one per group of five days) with sixteen volunteers. Enamel blocks (n = 256) were allocated to groups according to the treatment: Palm oil; Palm oil plus Sn solution; Sn solution - positive control; and Deionized water - negative control. Half of the enamel blocks of each group was subjected to erosion and the other half to erosion + abrasion. The daily ex vivo protocol consisted of four citric acid immersions (2 min). Before the first and third acid exposure, the blocks were treated with the test solutions (1 drop/block) for 1 min followed by acid immersion and abrasive challenge (toothpaste was applied on all blocks and half were brushed for 15 s/block). Enamel loss was quantified profilometrically and data were analyzed by two-way ANOVA and Tukey's test (p < 0.05).
A significant difference was found for type of treatment (p < 0.001); wear condition (p = 0.38) and the treatment x condition interaction (p = 0.33) was non-significant. Palm oil associated or not to Sn solution significantly reduced enamel wear in comparison with the negative control but did not differ from the positive control (p > 0.05).
Palm oil was able to prevent enamel loss under erosive and erosive + abrasive challenges in a similar extend to stannous-containing commercial solution.
棕榈油已被证明具有预防体外初始侵蚀脱矿的潜力。本原位研究评估了单独使用棕榈油或与含锡（Sn）溶液联合使用对预防侵蚀/磨损挑战导致的牙釉质损失的效果。
这项单盲、随机、交叉原位/离体研究分为四个阶段（每组为期五天）进行，共有 16 名志愿者参与。根据处理方法将牙釉质块（n=256）分配到以下组中：棕榈油；棕榈油加 Sn 溶液；Sn 溶液-阳性对照；去离子水-阴性对照。每组的一半牙釉质块接受侵蚀处理，另一半接受侵蚀+磨损处理。每日离体方案包括四次柠檬酸浸泡（2 分钟）。在第一次和第三次酸暴露之前，将块用测试溶液（1 滴/块）处理 1 分钟，然后进行酸浸泡和磨损挑战（所有块上都涂抹牙膏，一半块用牙刷刷牙 15 秒/块）。用轮廓仪定量测量牙釉质损失，用双因素方差分析和 Tukey 检验分析数据（p<0.05）。
处理类型（p<0.001）、磨损情况（p=0.38）和处理x条件相互作用（p=0.33）有显著差异。棕榈油与或不与 Sn 溶液联合使用与阴性对照相比显著减少了牙釉质磨损，但与阳性对照无差异（p>0.05）。
棕榈油能够在侵蚀和侵蚀+磨损挑战下预防牙釉质损失，其效果与含 Sn 的商业溶液相似。
