Moretto M J, Delbem A C B, Manarelli M M, Pessan J P, Martinhon C C R
Department of Pediatric Dentistry and Public Health, Araçatuba Dental School, UNESP - Univ. Estadual Paulista, Araçatuba, São Paulo, Brazil.
J Dent. 2013 Dec;41(12):1302-6. doi: 10.1016/j.jdent.2013.09.008. Epub 2013 Oct 3.
To evaluate the effect of fluoride (F) varnishes supplemented or not with sodium trimetaphosphate (TMP) on enamel erosive wear followed or not by abrasion in situ.
Ten volunteers were selected and randomly divided into four groups, according to the varnishes tested: placebo (no F or TMP), 5% NaF (positive control), 2.5% NaF and 2.5% NaF/5% TMP. Enamel blocks (n=4) were mounted in palatal devices and received an application of each test varnish, following a double-blind, crossover protocol. After 6h, varnishes were completely removed and the blocks were subjected to erosive challenges by ex vivo immersion in citric acid (5 min, 4×/dia, 5 days). Following, half of the blocks were subjected to abrasion by brushing with a placebo dentifrice slurry for 15s. Enamel wear (μm), surface hardness (SHf) and cross-sectional hardness (ΔKHN) were assessed after each experimental period. Results were analyzed by ANOVA, Student-Newman-Keuls's test and Pearson correlation coefficient (p<0.05).
The fluoride varnish supplemented with TMP promoted significantly lower wear and ΔKHN when compared to the other groups after erosive challenges, followed or not by abrasion (p<0.05). As for (SHf) the fluoride varnish supplemented with TMP promoted similar results to the 5% NaF product, being significantly higher than the remaining groups after erosive and erosive+abrasive challenges (p<0.05).
TMP significantly enhanced the effects of F on enamel wear after erosive challenges, followed or not by abrasion.
评估添加或不添加三聚偏磷酸钠(TMP)的氟化物(F)清漆对原位继或不继以磨损后的牙釉质侵蚀性磨损的影响。
选取10名志愿者,根据测试的清漆随机分为四组:安慰剂组(不含F或TMP)、5% NaF组(阳性对照组)、2.5% NaF组和2.5% NaF/5% TMP组。将牙釉质块(n = 4)安装在上腭装置中,并按照双盲、交叉方案接受每种测试清漆的涂抹。6小时后,将清漆完全去除,然后通过体外浸泡在柠檬酸中(5分钟,每天4次,共5天)对牙釉质块进行侵蚀性挑战。随后,一半的牙釉质块用安慰剂牙膏糊刷牙15秒进行磨损处理。在每个实验阶段后评估牙釉质磨损(μm)、表面硬度(SHf)和横截面硬度(ΔKHN)。结果通过方差分析、Student-Newman-Keuls检验和Pearson相关系数进行分析(p<0.05)。
与其他组相比,添加TMP的氟化物清漆在侵蚀性挑战继或不继以磨损后,磨损和ΔKHN显著更低(p<0.05)。至于(SHf),添加TMP的氟化物清漆产生的结果与5% NaF产品相似,在侵蚀和侵蚀+磨损挑战后显著高于其余组(p<0.05)。
TMP显著增强了F对侵蚀性挑战继或不继以磨损后的牙釉质磨损的影响。