Allanson Benjamin M, Low Tsu-Hui, Clark Jonathan R, Gupta Ruta
Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Building 94, Missenden Road, Via John Hopkins Drive, Camperdown, 2050, NSW, Australia.
Sydney Head and Neck Cancer Institute, Head and Neck Surgery Chris O'Brien Lifehouse, Sydney, NSW, Australia.
Head Neck Pathol. 2018 Sep;12(3):407-418. doi: 10.1007/s12105-018-0908-4. Epub 2018 Aug 1.
Squamous cell carcinoma (SCC) is the most common primary malignancy to affect the temporal bone, including primary cutaneous SCC of the pinna, external auditory canal, middle and inner ear. This anatomically complex region generates complicated three-dimensional specimens that can be a challenge for macroscopic and microscopic pathologic assessment. A universally accepted staging classification for these malignancies is still to be established. A brief summary of the regional anatomy, etiology and epidemiology, presentation and diagnosis, radiologic assessment and treatment follows with a review of the pathologic assessment of the different types of specimens generated and an update on staging for SCC of the temporal bone.
鳞状细胞癌（SCC）是最常见的累及颞骨的原发性恶性肿瘤，包括耳廓、外耳道、中耳和内耳的原发性皮肤SCC。这个解剖结构复杂的区域会产生复杂的三维标本，这对宏观和微观病理评估来说可能是一项挑战。这些恶性肿瘤的普遍接受的分期分类仍有待确立。以下是区域解剖、病因学和流行病学、临床表现和诊断、放射学评估及治疗的简要概述，并对所产生的不同类型标本的病理评估进行了回顾，以及颞骨SCC分期的最新情况。
