Takehara Hiroshi, Kodama Ken, Momozane Toru, Takeda Masashi, Shigetsu Kaichi, Kishima Hiroki
Department of Thoracic Surgery Yao Municipal Hospital Yao Japan.
Department of Pathology Yao Municipal Hospital Yao Japan.
Clin Case Rep. 2024 Sep 16;12(9):e9459. doi: 10.1002/ccr3.9459. eCollection 2024 Sep.
An 80-year-old never-smoking woman, who underwent radiotherapy in combination with simultaneous intra-arterial chemotherapy for external auditory canal squamous cell carcinoma (SCC) 10 years ago, was referred to our department due to a painful huge chest wall tumor. We conducted surgical resection combined with the right upper lobe and chest wall including the 3rd to 5th ribs and affected serratus anterior muscle. Histologically, atypical keratotic cells with the same morphology as external auditory canal SCC proliferated without the figure of carcinoma in situ or squamous dysplasia of the bronchial epithelium of the lung parenchyma adjacent to the tumor. If long-term imaging follow-up had been performed, it would have been easier to detect it early and differentiate it from metastasis or primary lung cancer.
一名80岁从不吸烟的女性,10年前因外耳道鳞状细胞癌接受了放疗并同时进行动脉内化疗,因出现疼痛性巨大胸壁肿瘤而被转诊至我科。我们进行了手术切除,范围包括右上叶、胸壁(第3至5肋骨)及受累的前锯肌。组织学检查显示,具有与外耳道鳞状细胞癌相同形态的非典型角化细胞增殖,未发现原位癌或肿瘤邻近肺实质支气管上皮的鳞状发育异常。如果进行长期影像学随访,将更容易早期发现并将其与转移瘤或原发性肺癌区分开来。