The mouse egg's receptor for sperm: what is it and how does it work?

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作者信息

Wassarman P M, Bleil J D, Florman H M, Greve J M, Roller R J, Salzmann G S, Samuels F G

出版信息

Cold Spring Harb Symp Quant Biol. 1985;50:11-9. doi: 10.1101/sqb.1985.050.01.004.

DOI:10.1101/sqb.1985.050.01.004

PMID:3006984

Abstract

摘要

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The mouse egg's receptor for sperm: what is it and how does it work?

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Effects of a phorbol ester on mouse eggs: dissociation of sperm receptor activity from acrosome reaction-inducing activity of the mouse zona pellucida protein, ZP3.佛波酯对小鼠卵子的影响：小鼠透明带蛋白ZP3的精子受体活性与顶体反应诱导活性的解离

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Nature of the mouse egg's receptor for sperm.小鼠卵子精子受体的性质。

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Induction of acrosome reactions by the human zona pellucida.人透明带诱导顶体反应。

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Status of the rat acrosome during sperm-zona pellucida interactions.精子与透明带相互作用过程中大鼠顶体的状态。

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Secretion and assembly of zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs for mZP2 and mZP3.用针对小鼠透明带糖蛋白2（mZP2）和小鼠透明带糖蛋白3（mZP3）的表位标记互补DNA（cDNA）显微注射生长中的小鼠卵母细胞后，其透明带糖蛋白的分泌与组装。

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Mutant female mice carrying a single mZP3 allele produce eggs with a thin zona pellucida, but reproduce normally.携带单个mZP3等位基因的突变雌性小鼠产生的卵子透明带较薄，但仍能正常繁殖。

Proc Biol Sci. 1997 Mar 22;264(1380):323-8. doi: 10.1098/rspb.1997.0046.

Sperm-egg recognition in the mouse: characterization of sp56, a sperm protein having specific affinity for ZP3.小鼠中的精卵识别：sp56的特性，一种对ZP3具有特异性亲和力的精子蛋白。

J Cell Biol. 1994 May;125(4):867-78. doi: 10.1083/jcb.125.4.867.

Transgenic mice with reduced numbers of functional sperm receptors on their eggs reproduce normally.卵子上功能性精子受体数量减少的转基因小鼠能够正常繁殖。

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Current ideas on the significance of protein glycosylation.关于蛋白质糖基化意义的当前观点。

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Galactose at the nonreducing terminus of O-linked oligosaccharides of mouse egg zona pellucida glycoprotein ZP3 is essential for the glycoprotein's sperm receptor activity.小鼠卵透明带糖蛋白ZP3的O-连接寡糖非还原端的半乳糖对于该糖蛋白的精子受体活性至关重要。

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Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning.通过基因组克隆确定的小鼠精子受体多肽的一级结构。

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Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction.有证据表明，ZP3引起的小鼠精子受体聚集会触发顶体反应。

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Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3--the mouse sperm receptor.编码透明带糖蛋白ZP3（小鼠精子受体）的基因的核苷酸序列。

Nucleic Acids Res. 1989 Apr 11;17(7):2861-3. doi: 10.1093/nar/17.7.2861.

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