Sinclair-McBride Keneisha, Morelli Nicholas, Tembulkar Sahil, Graber Kelsey, Gonzalez-Heydrich Joseph, D'Angelo Eugene J
Department of Psychiatry, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
BMC Res Notes. 2018 Aug 10;11(1):568. doi: 10.1186/s13104-018-3680-3.
Suicidal thoughts and behaviors (STBs) are prevalent among youth with psychotic disorders (PD) relative to the general population. Recent research now suggests that STBs may present during the prodromal phase of the disease, or the clinical high risk (CHR) state. While this knowledge is important for the development of suicide prevention strategies in adolescent and adult populations, it remains unclear whether risk for suicide extends to children with or at risk for psychosis. The current study is an extension of previous work assessing STBs in youth across the psychosis continuum. We examine STBs in 37 CHR and PD children ages 7-13 years old, and further explore the prodromal symptom correlates of STB severity among CHR children.
CHR and PD children endorsed STBs with a frequency and severity similar to what is observed in older CHR and PD populations. A number of children had never previously vocalized their suicidal plans or intent. Among CHR children, Social Anhedonia and Odd Behavior or Appearance were significantly correlated with STB severity. These findings underscore the importance of screening for STBs even in young children presenting with psychotic symptoms.
与普通人群相比,自杀观念和行为(STB)在患有精神障碍(PD)的青少年中更为普遍。最近的研究表明,STB可能出现在疾病的前驱期,即临床高危(CHR)状态。虽然这一认识对于制定青少年和成人自杀预防策略很重要,但自杀风险是否也适用于患有精神病或有精神病风险的儿童仍不清楚。本研究是先前评估精神病连续体中青少年STB的工作的延伸。我们对37名7至13岁的CHR和PD儿童进行了STB检查,并进一步探讨了CHR儿童中STB严重程度的前驱症状相关性。
CHR和PD儿童认可STB的频率和严重程度与在年龄较大的CHR和PD人群中观察到的相似。许多儿童以前从未说出过他们的自杀计划或意图。在CHR儿童中,社交快感缺失和怪异行为或外表与STB严重程度显著相关。这些发现强调了即使在出现精神病症状的幼儿中筛查STB的重要性。