Laboratory of Parasitology-Mycology of the Rabta Hospital of Tunis, 1082 Tunis, Tunisia.
Laboratory of Parasitology-Mycology of the Rabta Hospital of Tunis, 1082 Tunis, Tunisia.
J Mycol Med. 2018 Dec;28(4):651-654. doi: 10.1016/j.mycmed.2018.07.005. Epub 2018 Aug 11.
Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts or non-dermatophyte molds. The aim of our study was to describe the epidemiological features of onychomycoses encountered in the Tunis region. A retrospective study concerned 3458 cases of onychomycosis, confirmed by direct examination and/or a positive culture, was conducted in Parasitology - Mycology Laboratory, Rabta hospital, over a five-year period (2012-2016). Our patients were aged 1 to 85; more than half of the patients were aged over 60 years with a female predominance (67%). Toenail infections were most common, observed in 2702 cases (78%). Direct examination was positive in 3284 cases (95%), culture in 2409 cases (69.6%); these two examinations were positive simultaneously in 2235 cases (64.6%). The causative agents of these onychomycoses were dominated by the genus Candida in fingernails: Candida albicans (55.6%), Candida tropicalis (8.5%) and Candida parapsilosis (8.2%) were the most frequently incriminated species; while in toenail lesions, Trichophyton rubrum was by far the most frequently isolated species (96.8%). Our results join the literature; onychomycosis is a pathology of the adult, mainly candidosic etiology in hands and dermatophytic in feet.
甲真菌病是由真菌引起的指甲感染，包括皮肤癣菌、酵母菌或非皮肤癣菌霉菌。我们的研究目的是描述突尼斯地区甲真菌病的流行病学特征。一项回顾性研究涉及 3458 例经直接检查和/或阳性培养证实的甲真菌病病例，该研究在拉巴特医院寄生虫学-真菌学实验室进行，时间跨度为 5 年（2012-2016 年）。我们的患者年龄为 1 至 85 岁；超过一半的患者年龄在 60 岁以上，女性居多（67%）。趾甲感染最常见，见于 2702 例（78%）。直接检查阳性 3284 例（95%），培养阳性 2409 例（69.6%）；这两种检查同时阳性 2235 例（64.6%）。这些甲真菌病的病原体主要以指甲中的假丝酵母菌属为主：白色假丝酵母菌（55.6%）、热带假丝酵母菌（8.5%）和近平滑假丝酵母菌（8.2%）是最常被归咎的物种；而在趾甲病变中，红色毛癣菌是迄今为止最常分离到的物种（96.8%）。我们的结果与文献相符；甲真菌病是一种成人疾病，主要在手为酵母菌病因，在脚为皮肤癣菌病因。
