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乌干达卡波西肉瘤的更多经验

Further experience with Kaposi's sarcoma in Uganda.

作者信息

Serwadda D, Carswell W, Ayuko W O, Wamukota W, Madda P, Downing R G

出版信息

Br J Cancer. 1986 Apr;53(4):497-500. doi: 10.1038/bjc.1986.78.

DOI:10.1038/bjc.1986.78
PMID:3011052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2001431/
Abstract

Four Ugandan patients (1 women, 3 men) with generalized Kaposi's sarcoma (KS) were seen in the Uganda Cancer Institute between October 1983 and December 1984. They presented with generalized lymphadenopathy, plaques/nodules on the body, general swelling of the head, oral and visceral involvement and respiratory distress. Initial responses to adriamycin as a single or a combination chemotherapy of actinomycin D, vincristine, adriamycin and imidazole carboxamide appeared to be favourable but no sustained response was obtained. Serological tests for human T-lymphotropic virus (HTLV-II) antibodies were positive in all 4 cases.

摘要

1983年10月至1984年12月期间,乌干达癌症研究所接待了4名患有全身性卡波西肉瘤(KS)的患者(1名女性,3名男性)。他们表现为全身性淋巴结肿大、身体上出现斑块/结节、头部普遍肿胀、口腔和内脏受累以及呼吸窘迫。作为单一化疗药物或与放线菌素D、长春新碱、阿霉素和咪唑甲酰胺联合化疗时,阿霉素的初始反应似乎良好,但未获得持续缓解。所有4例患者的人类嗜T淋巴细胞病毒(HTLV-II)抗体血清学检测均为阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2001431/e3c1c38188c3/brjcancer00528-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2001431/dd2e56dd5e42/brjcancer00528-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2001431/e3c1c38188c3/brjcancer00528-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2001431/dd2e56dd5e42/brjcancer00528-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7229/2001431/e3c1c38188c3/brjcancer00528-0046-a.jpg

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1
Further experience with Kaposi's sarcoma in Uganda.乌干达卡波西肉瘤的更多经验
Br J Cancer. 1986 Apr;53(4):497-500. doi: 10.1038/bjc.1986.78.
2
HTLV-III serology distinguishes atypical and endemic Kaposi's sarcoma in Africa.人类嗜T淋巴细胞病毒III型血清学可区分非洲的非典型和地方性卡波西肉瘤。
Lancet. 1985 Feb 16;1(8425):359-61. doi: 10.1016/s0140-6736(85)91383-2.
3
Lymphadenopathic type of Kaposi's sarcoma in a Ugandan child seropositive for LAV/HTLV-III antibodies.一名乌干达儿童的卡波西肉瘤淋巴结病型,该儿童LAV/HTLV - III抗体血清学呈阳性。
J Trop Med Hyg. 1987 Apr;90(2):93-4.
4
Kaposi's sarcoma and HTLV-III: a study in Nigerian adult males.卡波西肉瘤与人类嗜T淋巴细胞病毒III型:一项针对尼日利亚成年男性的研究。
J R Soc Med. 1986 Sep;79(9):510-4. doi: 10.1177/014107688607900905.
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[Kaposi sarcoma in acquired immune deficiency syndrome (AIDS). I: Clinical findings and laboratory diagnosis].[获得性免疫缺陷综合征(艾滋病)中的卡波西肉瘤。I:临床表现与实验室诊断]
Laryngol Rhinol Otol (Stuttg). 1985 Aug;64(8):418-22.
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Lymphadenopathic form of Kaposi's sarcoma (KS) in an African child. No evidence for acquired immunodeficiency syndrome (AIDS).一名非洲儿童的卡波西肉瘤(KS)淋巴结病型。无获得性免疫缺陷综合征(AIDS)证据。
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Arch Intern Med. 1996 Jan 22;156(2):202-4.
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J Bioeth Inq. 2014 Dec;11(4):467-78. doi: 10.1007/s11673-014-9577-5. Epub 2014 Oct 11.
3
Seroprevalence of Human herpesvirus 8 (HHV-8) and incidence of Kaposi's sarcoma in Iran.

本文引用的文献

1
Kaposi's sarcoma: clinical features, experience in Uganda.
Antibiot Chemother (1971). 1981;29:59-67. doi: 10.1159/000397440.
2
Management of Kaposi's sarcoma. Chemotherapy II.卡波西肉瘤的治疗。化疗II。
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Prevalence of antibody to human T-lymphotropic virus type III in AIDS and AIDS-risk patients in Britain.英国艾滋病患者及艾滋病高危人群中抗人类Ⅲ型嗜T淋巴细胞病毒抗体的流行情况。
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伊朗人类疱疹病毒 8 (HHV-8)的血清流行率和卡波西肉瘤的发病率。
Infect Agent Cancer. 2011 Apr 28;6:5. doi: 10.1186/1750-9378-6-5.
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Aggressive Kaposi's sarcoma in Zambia, 1983.1983年赞比亚侵袭性卡波西肉瘤。
Lancet. 1984 Jun 16;1(8390):1318-20. doi: 10.1016/s0140-6736(84)91818-x.
5
Acquired immunodeficiency syndrome is an opportunistic infection and Kaposi's sarcoma results from secondary immune stimulation.获得性免疫缺陷综合征是一种机会性感染,卡波西肉瘤是继发免疫刺激的结果。
Lancet. 1983 Jul 9;2(8341):78-81. doi: 10.1016/s0140-6736(83)90062-4.
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Kaposi's sarcoma in Uganda: a clinico-pathological study.乌干达的卡波西肉瘤:一项临床病理研究。
Int J Cancer. 1971 Jul 15;8(1):122-35. doi: 10.1002/ijc.2910080116.
7
Studies in Kaposi's sarcoma. Postmortem findings and disease patterns in women.卡波西肉瘤的研究。女性的尸检结果及疾病模式。
Cancer. 1972 Sep;30(3):854-67. doi: 10.1002/1097-0142(197209)30:3<854::aid-cncr2820300337>3.0.co;2-a.
8
Effective treatment of Kaposi's sarcoma with 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388).用5-(3,3-二甲基-1-三氮烯基)咪唑-4-甲酰胺(NSC-45388)有效治疗卡波西肉瘤。
Cancer Chemother Rep. 1973 Feb;57(1):65-71.
9
Treatment of Kaposi's sarcoma by combination of actinomycin-D, vincristine and imidazole carboxamide (nsc-45388): results of a randomized clinical trial.放线菌素-D、长春新碱和咪唑甲酰胺(NSC-45388)联合治疗卡波西肉瘤:一项随机临床试验的结果
Int J Cancer. 1974 Nov 15;14(5):649-56. doi: 10.1002/ijc.2910140512.
10
Kaposi's sarcoma presenting with diarrhea and protein-losing enteropathy.以腹泻和蛋白丢失性肠病为表现的卡波西肉瘤。
Gastroenterology. 1974 Nov;67(5):996-1000.