Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Deportment of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Biomed Pharmacother. 2018 Oct;106:1499-1505. doi: 10.1016/j.biopha.2018.07.084. Epub 2018 Jul 24.
Developments in nanotechnology have expanded novel nanoparticles for several applications, including cosmetic topical preparation. The aim of this article was to review recent literature on percutaneous delivery of cosmetics active ingredient by nanoparticles. The main focus here, is on lipid based nanoparticles since they are of great importance in skin cargo delivery and have vast application in current cosmetic formulations. Data were collected via electronic databases using MeSH keywords, including nanoparticles, lipid particles, cosmetic, dermal delivery and combinations of these words. According to literature nanoparticles play a major role in improving the usefulness of cosmetics. They are able to improve the physiochemical stability of the skin based cosmetic products. Based on data, lipid nanostructures can be added to current cosmetic formulations without any significant problem due to their physical stability and compatibility with other ingredients. However, due to their basically risky nature of nanoparticles, their risk assessment should be taken into consideration.
纳米技术的发展为多种应用扩展了新型纳米粒子，包括化妆品的局部制剂。本文旨在综述纳米粒子经皮传递化妆品活性成分的最新文献。本文的主要重点是基于脂质的纳米粒子，因为它们在皮肤货物传递中非常重要，并在当前化妆品配方中有广泛的应用。通过使用 MeSH 关键词的电子数据库收集数据，包括纳米粒子、脂质体、化妆品、经皮传递和这些词的组合。根据文献，纳米粒子在提高化妆品的有用性方面发挥着重要作用。它们能够提高基于皮肤的化妆品产品的物理化学稳定性。基于这些数据，由于脂质纳米结构的物理稳定性和与其他成分的相容性，它们可以添加到当前的化妆品配方中，而不会出现任何重大问题。然而，由于纳米粒子本质上存在风险，应考虑对其进行风险评估。
