Basnet Buddha Bahadur, Liu Li, Bao Li, Liu Hongwei
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.
International College, University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Mycology. 2017 May 24;8(2):111-124. doi: 10.1080/21501203.2017.1324529. eCollection 2017.
Medicinal mushroom sp. is considered to be a key source for the production of therapeutic agents. Our current review indicates that a limited number (<19%; 79 out of >430) of isolated compounds have been tested and known to be active against several microorganisms and parasites. In this review, we aim to summarise all the antimicrobial and anti-parasitic works on sp. displayed on web of science, google scholar and endnote X7 from 1932 to August 2016. We further present and discuss the structure of active compounds against microorganisms and parasites. In addition, we also discuss the possible further research to identify lead compounds from sp. as a novel strategy to combat the potential global emergence of bad bugs and parasites.
药用蘑菇物种被认为是治疗药物生产的关键来源。我们目前的综述表明，已测试的分离化合物数量有限（<19%；超过430种中的79种），并且已知对几种微生物和寄生虫具有活性。在本综述中，我们旨在总结1932年至2016年8月在科学网、谷歌学术和EndNote X7上展示的关于该物种的所有抗菌和抗寄生虫研究。我们还进一步展示并讨论了针对微生物和寄生虫的活性化合物的结构。此外，我们还讨论了从该物种中鉴定先导化合物作为应对潜在全球有害病菌和寄生虫出现的新策略的可能进一步研究。
