Lupi Saturnino Marco, Rodriguez Y Baena Arianna, Todaro Claudia, Ceccarelli Gabriele, Rodriguez Y Baena Ruggero
Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Department of Public Health, Experimental Medicine and Forensic, Human Anatomy Unit, University of Pavia, Pavia, Italy.
Case Rep Dent. 2018 Jul 24;2018:3023096. doi: 10.1155/2018/3023096. eCollection 2018.
This case report discusses about an innovative bone regeneration method that involves the use of autologous periosteal micrografts, which were used for a maxillary sinus floor lift in a 52-year-old female patient. This method allows for harvesting of a graft that is to be seeded on a PLGA scaffold and involves collection of a very little amount of palatal periosteal tissue in the same surgical site after elevation of a flap and disaggregation of it by using a Rigenera® filter. Histological samples collected at the time of implant installation demonstrate a good degree of bone regeneration. The clinical and radiographic outcomes at the 3-year follow-up visit showed an adequate stability of hard and soft tissues around the implants. This report demonstrates the possibility to obtain a sufficient quality and quantity of bone with a progenitor cell-based micrograft and in turn make the site appropriate for an implant-supported rehabilitation procedure, with stable results over a period of two years.
本病例报告讨论了一种创新的骨再生方法,该方法涉及使用自体骨膜微移植,用于一名52岁女性患者的上颌窦底提升术。这种方法允许采集将接种在聚乳酸-羟基乙酸共聚物(PLGA)支架上的移植物,并且在掀起皮瓣后,通过使用Rigenera®过滤器在同一手术部位收集极少量的腭骨膜组织并将其分解。在植入种植体时采集的组织学样本显示出良好程度的骨再生。3年随访时的临床和影像学结果表明种植体周围软硬组织具有足够的稳定性。本报告证明了利用基于祖细胞的微移植获得足够质量和数量的骨的可能性,进而使该部位适合种植体支持的修复程序,并在两年期间取得稳定的结果。