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Management of Acute Respiratory Distress Syndrome with H1N1 Influenza Virus in Pregnancy: Successful Mechanical Ventilation and Weaning with Airway Pressure Release Ventilation.妊娠期甲型H1N1流感病毒所致急性呼吸窘迫综合征的管理：应用气道压力释放通气成功进行机械通气及撤机
Turk J Anaesthesiol Reanim. 2018 Feb;46(1):62-65. doi: 10.5152/TJAR.2017.33044. Epub 2018 Feb 1.
2
Clinical course of ICU patients with severe pandemic 2009 influenza A (H1N1) pneumonia: single center experience with proning and pressure release ventilation.重症监护病房严重大流行性 2009 流感 A（H1N1）肺炎患者的临床病程：俯卧位和压力释放通气的单中心经验。
J Intensive Care Med. 2012 May-Jun;27(3):184-90. doi: 10.1177/0885066610396168. Epub 2011 May 18.
3
Airway pressure-release ventilation in pregnant patients with acute respiratory distress syndrome: a novel strategy.急性呼吸窘迫综合征孕妇的气道压力释放通气：一种新策略。
Respir Care. 2009 Oct;54(10):1405-8.
4
Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome.早期应用气道压力释放通气可能会降低急性呼吸窘迫综合征患者机械通气的时间。
Intensive Care Med. 2017 Nov;43(11):1648-1659. doi: 10.1007/s00134-017-4912-z. Epub 2017 Sep 22.
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Management of acute respiratory distress syndrome in a French Bulldog using airway pressure release ventilation.使用气道压力释放通气法对一只法国斗牛犬急性呼吸窘迫综合征的治疗
J Vet Emerg Crit Care (San Antonio). 2013 Jul-Aug;23(4):447-54. doi: 10.1111/vec.12071. Epub 2013 Jul 15.
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Clinical research about airway pressure release ventilation for moderate to severe acute respiratory distress syndrome.关于气道压力释放通气治疗中重度急性呼吸窘迫综合征的临床研究。
Eur Rev Med Pharmacol Sci. 2016 Jun;20(12):2634-41.
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Successful Ventilation of Acute Respiratory Distress Syndrome Complicated by Pneumothorax Using Airway Pressure Release Ventilation: A Case Report.使用气道压力释放通气成功治疗急性呼吸窘迫综合征合并气胸：一例报告
Indian J Crit Care Med. 2019 Sep;23(9):437-438. doi: 10.5005/jp-journals-10071-23242.
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Severe Pediatric Acute Respiratory Distress Syndrome Due to Scrub Typhus: Successful Ventilation with Airway Pressure Release Ventilation Mode after Becoming Refractory to Protective Ventilation.恙虫病所致重症小儿急性呼吸窘迫综合征：在保护性通气无效后采用气道压力释放通气模式成功通气
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[Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome caused by novel 2009 influenza A (H1N1) virus].[体外膜肺氧合治疗2009年新型甲型H1N1流感病毒所致严重急性呼吸窘迫综合征]
Zhonghua Yi Xue Za Zhi. 2011 Dec 13;91(46):3262-6.
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Respiratory controversies in the critical care setting. Does airway pressure release ventilation offer important new advantages in mechanical ventilator support?重症监护环境中的呼吸争议。气道压力释放通气在机械通气支持方面是否具有重要的新优势？
Respir Care. 2007 Apr;52(4):452-8; discussion 458-60.

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1
Pregnancy enhances antiviral immunity independent of type I IFN but dependent on IL-17-producing γδ T cells in the nasal mucosa.妊娠增强了抗病毒免疫，这种免疫独立于 I 型 IFN，但依赖于鼻黏膜中产生 IL-17 的 γδ T 细胞。
Sci Adv. 2024 Sep 27;10(39):eado7087. doi: 10.1126/sciadv.ado7087.
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Role of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange Therapy in the Management of a Twin Pregnancy with H1N1 Infection in Early Acute Respiratory Distress Syndrome.经鼻湿化快速充气通气交换疗法在一例双胎妊娠合并H1N1感染早期急性呼吸窘迫综合征管理中的作用
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3
Rhinovirus-associated severe acute respiratory distress syndrome (ARDS) managed with airway pressure release ventilation (APRV).采用气道压力释放通气（APRV）治疗的鼻病毒相关性严重急性呼吸窘迫综合征（ARDS）
Trauma Surg Acute Care Open. 2019 Jul 15;4(1):e000322. doi: 10.1136/tsaco-2019-000322. eCollection 2019.

本文引用的文献

1
Clinical research about airway pressure release ventilation for moderate to severe acute respiratory distress syndrome.关于气道压力释放通气治疗中重度急性呼吸窘迫综合征的临床研究。
Eur Rev Med Pharmacol Sci. 2016 Jun;20(12):2634-41.
2
Respiratory Failure and Mechanical Ventilation in the Pregnant Patient.妊娠患者的呼吸衰竭与机械通气
Crit Care Clin. 2016 Jan;32(1):85-95. doi: 10.1016/j.ccc.2015.08.001. Epub 2015 Oct 23.
3
Airway pressure release ventilation and respiratory failure during pregnancy. A report of three cases.
J Reprod Med. 2015 Jan-Feb;60(1-2):65-70.
4
Mechanical ventilation during pregnancy: sedation, analgesia, and paralysis.孕期机械通气：镇静、镇痛与麻痹
Clin Obstet Gynecol. 2014 Dec;57(4):844-50. doi: 10.1097/GRF.0000000000000064.
5
Ventilator-associated lung injury during assisted mechanical ventilation.辅助机械通气期间的呼吸机相关性肺损伤。
Semin Respir Crit Care Med. 2014 Aug;35(4):409-17. doi: 10.1055/s-0034-1382153. Epub 2014 Aug 8.
6
Airway pressure release ventilation: improving oxygenation: indications, rationale, and adverse events associated with airway pressure release ventilation in patients with acute respiratory distress syndrome for advance practice nurses.气道压力释放通气：改善氧合：急性呼吸窘迫综合征患者气道压力释放通气的适应症、原理及相关不良事件，供高级实践护士参考
Dimens Crit Care Nurs. 2013 Sep-Oct;32(5):222-8. doi: 10.1097/DCC.0b013e3182a076ce.
7
Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury.早期气道压力释放通气预防 ARDS-一种新的肺损伤预防方法。
Shock. 2013 Jan;39(1):28-38. doi: 10.1097/SHK.0b013e31827b47bb.
8
Airway pressure release ventilation: what do we know?气道压力释放通气：我们了解多少？
Respir Care. 2012 Feb;57(2):282-92. doi: 10.4187/respcare.01238. Epub 2011 Jul 12.
9
Airway pressure release ventilation: an alternative mode of mechanical ventilation in acute respiratory distress syndrome.气道压力释放通气：急性呼吸窘迫综合征的一种机械通气方式。
Cleve Clin J Med. 2011 Feb;78(2):101-10. doi: 10.3949/ccjm.78a.10032.
10
Prolonged propofol use in a critically ill pregnant patient.危重症孕妇中长时间使用异丙酚。
Ann Pharmacother. 2010 Dec;44(12):2018-22. doi: 10.1345/aph.1P427. Epub 2010 Nov 9.

妊娠期甲型H1N1流感病毒所致急性呼吸窘迫综合征的管理：应用气道压力释放通气成功进行机械通气及撤机

Management of Acute Respiratory Distress Syndrome with H1N1 Influenza Virus in Pregnancy: Successful Mechanical Ventilation and Weaning with Airway Pressure Release Ventilation.

作者信息

Küçük Mehtap Pehlivanlar, Öztürk Çağatay Erman, İlkaya Nazan Köylü, Eyüpoğlu Selin, Ülger Fatma, Şahinoğlu Ali Haydar

机构信息

Department of Anaesthesiology and Reanimation, Division of Intensive Care Medicine, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2018 Feb;46(1):62-65. doi: 10.5152/TJAR.2017.33044. Epub 2018 Feb 1.

DOI:10.5152/TJAR.2017.33044
PMID:30140503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5858892/
Abstract

In pregnancy, infection with H1N1 influenza virus may produce symptoms similar to infection with seasonal influenza virus. Patients may rarely come with a clinical condition causing severe acute respiratory distress syndrome (ARDS) and death. Therefore, mechanical-ventilation strategies to manage these events are vital. We report a case of ARDS after an infection with H1N1 influenza A in a 33-year-old patient pregnant at 27-weeks. The ARDS was successfully managed by airway pressure release ventilation (APRV). APRV can be used successfully as an alternative to conventional mechanical ventilation modes in pregnant patients experiencing severe respiratory failure.

摘要

在孕期，感染H1N1流感病毒可能产生与感染季节性流感病毒相似的症状。患者极少会出现导致严重急性呼吸窘迫综合征（ARDS）及死亡的临床状况。因此，应对这些情况的机械通气策略至关重要。我们报告一例27周妊娠的33岁患者感染甲型H1N1流感后发生ARDS的病例。该ARDS通过气道压力释放通气（APRV）成功得到处理。在患有严重呼吸衰竭的妊娠患者中，APRV可成功用作传统机械通气模式的替代方法。