Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Chem Commun (Camb). 2018 Sep 11;54(73):10324-10327. doi: 10.1039/c8cc05979a.
A new protocol for nucleophilic amination of methoxypyridines and their derivatives was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The method offers a concise access to various aminopyridines which are potentially of medicinal interest.
开发了一种使用氢化钠（NaH）并加入碘化锂（LiI）作为亲核胺化试剂来实现甲氧基吡啶及其衍生物的新方法。该方法提供了一种简洁的途径来制备具有潜在药用价值的各种氨基吡啶。
