Gao Hong, Liu Dong-E, Li Yumei, Tang Jing, Hu Shimin, Wu Xinrui, Tian Zhengwen, Tan Hongzhuan
Department of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha School of Nursing, University of South China, Hengyang Reproductive Medicine Centre, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Medicine (Baltimore). 2018 Aug;97(34):e12068. doi: 10.1097/MD.0000000000012068.
The aim of this study was to describe the size and the shape of gravida-0 uteri in infertile Chinese Han women according to age, height, and body mass index (BMI).Registered data obtained from the Department of Reproductive Medicine, Xiangya Hospital of Central South University, were collected and analyzed. The length, width, and anteroposterior diameter of the uteri of nonpregnant women aged 20 to 45 years were measured by transvaginal ultrasonography. Statistical analyses among different populations were conducted using a 1-way analysis of variance analysis or a Kruskal-Wallis H test.A total of 5726 primary infertile women were enrolled. The mean age of the sample group was 29.18 ± 4.22 years, and the mean BMI and the mean height of them were 21.51 ± 2.91 kg/m and 158.13 ± 4.71 cm, respectively. The mean uterine length, width, anteroposterior diameter, and L/W ratio were 49.33 ± 7.00 mm, 39.94 ± 7.23 mm, 44.95 ± 8.11 mm, and 1.2662 ± 0.2465, respectively. There were a statistically significant positive correlations between uterine length, width, anteroposterior diameter, and age in infertile women (all P < .001). Uterine L/W ratio gradually decreased with age, which was statistically significant (P < .001). The correlations between uterine length, width, anteroposterior diameter, and height were also considered statistically significant (all P < .001), while there was no correlation between L/W ratio and height. The results showed that uterine size and BMI had no statistical significance.The uterine length, width, and anteroposterior diameter gradually increased with increased age and height, but the increasing extents was different, and the uterine shape became rounder with age and had not changed with height in primary infertile women.
本研究旨在根据年龄、身高和体重指数（BMI）描述中国汉族不孕女性未孕子宫的大小和形态。收集并分析了从中南大学湘雅医院生殖医学科获取的登记数据。采用经阴道超声测量20至45岁未孕女性子宫的长度、宽度和前后径。不同人群之间的统计分析采用单因素方差分析或Kruskal-Wallis H检验。
共纳入5726例原发性不孕女性。样本组的平均年龄为29.18±4.22岁，平均BMI和平均身高分别为21.51±2.91kg/m和158.13±4.71cm。子宫平均长度、宽度、前后径和长/宽比分别为49.33±7.00mm、39.94±7.23mm、44.95±8.11mm和1.2662±0.2465。不孕女性子宫长度、宽度、前后径与年龄之间存在统计学显著正相关（均P<0.001）。子宫长/宽比随年龄逐渐降低，差异有统计学意义（P<0.001）。子宫长度、宽度、前后径与身高之间的相关性也具有统计学意义（均P<0.001），而长/宽比与身高之间无相关性。结果显示子宫大小与BMI无统计学意义。
原发性不孕女性的子宫长度、宽度和前后径随年龄和身高增加而逐渐增大，但增大程度不同，子宫形态随年龄变得更圆，而随身高无变化。
