Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), C/Nicolás Cabrera, 9, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Department of Food and Nutritional Sciences, The University of Reading, PO Box 226, Whiteknights, Reading RG6 6 AP, UK.
Carbohydr Polym. 2018 Nov 1;199:482-491. doi: 10.1016/j.carbpol.2018.07.041. Epub 2018 Jul 21.
The suitability of artichoke and sunflower by-products as renewable sources of pectic compounds with prebiotic potential was evaluated by studying their ability to modulate the human faecal microbiota in vitro. Bacterial populations and short-chain fatty acid (SCFA) production were measured. Reduction of the molecular weight of artichoke pectin resulted in greater stimulation of the growth of Bifidobacterium, Lactobacillus and Bacteroides/Prevotella, whilst this effect was observed only in Bacteroides/Prevotella for sunflower samples. In contrast, the degree of methoxylation did not have any impact on fermentability properties or SCFA production, regardless of the origin of pectic compounds. Although further in vivo studies should be conducted, either pectin or enzymatically-modified pectin from sunflower and artichoke by-products might be considered as prebiotic candidates for human consumption showing similar ability to promote the in vitro growth of beneficial gut bacteria as compared to well-recognized prebiotics such as inulin or fructo-oligosaccharides.
以菊苣和葵花籽副产物为可再生来源的果胶化合物具有益生元潜力，本研究评估了它们在体外调节人体粪便微生物群的能力。测量了细菌种群和短链脂肪酸 (SCFA) 的产生。菊苣果胶的分子量降低导致双歧杆菌、乳杆菌和拟杆菌/普雷沃氏菌的生长受到更大的刺激，而这种作用仅在葵花籽样品中观察到拟杆菌/普雷沃氏菌。相比之下，无论果胶化合物的来源如何，甲氧基化程度都不会影响发酵性能或 SCFA 产生。尽管还需要进行进一步的体内研究，但葵花籽和菊苣副产物中的果胶或酶改性果胶可以被认为是人类食用的益生元候选物，它们具有与公认的益生元（如菊粉或果寡糖）相似的促进有益肠道细菌体外生长的能力。
