Hunzelmann Nicolas
Klinik für Dermatologie und Venerologie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Hautarzt. 2018 Nov;69(11):901-907. doi: 10.1007/s00105-018-4258-7.
Systemic sclerosis (scleroderma) is a severe, chronic inflammatory connective tissue disease involving the skin, musculoskeletal system, and several internal organs. The heterogeneity of its presentation and course are a particular challenge for the treating physician. As therapeutic options have improved considerably during recent years, various working groups have published consensus recommendations for the treatment of SSc. The aim of this overview is to present major aspects of these recommendations and embed them in a concept of modern interdisciplinary care for this often still devastating disease.
系统性硬化症（硬皮病）是一种严重的慢性炎症性结缔组织病，累及皮肤、肌肉骨骼系统和多个内脏器官。其临床表现和病程的异质性给治疗医生带来了特殊挑战。近年来，随着治疗选择有了显著改善，多个工作组已发布了系统性硬化症治疗的共识性建议。本综述的目的是介绍这些建议的主要方面，并将其纳入针对这种往往仍具破坏性疾病的现代跨学科护理理念之中。
