Sticherling Michael
Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
Internist (Berl). 2019 Aug;60(8):783-791. doi: 10.1007/s00108-019-0643-2.
Sclerosing skin manifestations are more a symptom than a diagnosis and must therefore be meticulously clarified. Systemic scleroderma as a multiorgan disease must be distinguished from localized scleroderma or morphea because in addition to a different clinical picture they have a different prognosis and necessitate other therapeutic procedures. Rare sclerosing skin diseases with implications for internal medicine are eosinophilic fasciitis, Buschke's scleredema adultorum, scleromyxedema and nephrogenic systemic fibrosis.
硬化性皮肤表现更多是一种症状而非诊断结果，因此必须进行细致的甄别。系统性硬化症作为一种多器官疾病，必须与局限性硬皮病或硬斑病区分开来，因为除了临床表现不同外，它们的预后也不同，且需要不同的治疗方法。对内科有影响的罕见硬化性皮肤病包括嗜酸性筋膜炎、成人布氏硬肿病、硬化黏液水肿和肾源性系统性纤维化。
