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米诺地尔治疗雄激素性脱发。

Minoxidil in the treatment of androgenetic alopecia.

机构信息

Applied Biology, Inc., Irvine, California.

出版信息

Dermatol Ther. 2018 Sep;31(5):e12686. doi: 10.1111/dth.12686. Epub 2018 Aug 28.

DOI:10.1111/dth.12686
PMID:30155952
Abstract

The National Institutes of Health (US NIH, 2018) estimates that in the US approximately 50 million men and 30 million women suffer from AGA (also known as pattern hair loss). Minoxidil is the only topical drug for the treatment of both female and male pattern hair loss. In the US, minoxidil is approved over-the-counter (OTC) at a maximum concentration of 5%. In this review, we summarize the findings of the pivotal studies used in support of the drug's approval as well as recent discoveries and novel developments in the use of minoxidil for the treatment of AGA.

摘要

美国国立卫生研究院(NIH)估计,在美国约有 5000 万男性和 3000 万女性患有 AGA(也称为模式性脱发)。米诺地尔是治疗女性和男性AGA 的唯一外用药物。在美国,米诺地尔的最大浓度为 5%,可在柜台上购买。在这篇综述中,我们总结了支持该药物批准的关键性研究结果,以及米诺地尔治疗 AGA 的最新发现和新进展。

相似文献

1
Minoxidil in the treatment of androgenetic alopecia.米诺地尔治疗雄激素性脱发。
Dermatol Ther. 2018 Sep;31(5):e12686. doi: 10.1111/dth.12686. Epub 2018 Aug 28.
2
Androgenetic alopecia and current methods of treatment.雄激素性脱发及其当前治疗方法。
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A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia.一项关于0.25%非那雄胺与3%米诺地尔混合外用溶液对比3%米诺地尔溶液治疗男性雄激素性脱发疗效和安全性的随机双盲对照研究。
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Topical Minoxidil: Systematic Review and Meta-Analysis of Its Efficacy in Androgenetic Alopecia.外用米诺地尔:其治疗雄激素性脱发疗效的系统评价与荟萃分析
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Mechanism of action of minoxidil in the treatment of androgenetic alopecia is likely mediated by mitochondrial adenosine triphosphate synthase-induced stem cell differentiation.米诺地尔治疗雄激素性脱发的作用机制可能是由线粒体三磷酸腺苷合酶诱导干细胞分化介导的。
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Topical fulvestrant solution has no effect on male and postmenopausal female androgenetic alopecia: results from two randomized, proof-of-concept studies.局部用氟维司群溶液对男性和绝经后女性雄激素性脱发无效:两项随机概念验证研究的结果
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Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis.非手术治疗雄激素性脱发的疗效:一项系统评价和网状Meta分析
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Male pattern baldness.男性型秃发
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Advances in Transdermal Delivery Systems for Treating Androgenetic Alopecia.治疗雄激素性脱发的透皮给药系统进展
Pharmaceutics. 2025 Jul 30;17(8):984. doi: 10.3390/pharmaceutics17080984.
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Analysis on the treatment compliance of patients with androgenetic alopecia and its influencing factors: based on the comparison between microneedle therapy and drug therapy.雄激素性脱发患者治疗依从性及其影响因素分析:基于微针疗法与药物疗法的比较
Arch Dermatol Res. 2025 Apr 3;317(1):670. doi: 10.1007/s00403-025-04211-0.
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Low dose oral minoxidil for the treatment of female pattern hair loss.
低剂量口服米诺地尔治疗女性型脱发
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Engineered Exosomes Biopotentiated Hydrogel Promote Hair Follicle Growth via Reprogramming the Perifollicular Microenvironment.工程化外泌体生物增强水凝胶通过重编程毛囊周围微环境促进毛囊生长。
Pharmaceutics. 2024 Jul 13;16(7):935. doi: 10.3390/pharmaceutics16070935.
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Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells for androgenetic alopecia treatment.仿生工程脂肪干细胞纳米囊泡热敏水凝胶增强毛囊乳头细胞自噬以治疗雄激素性脱发
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Patient perspectives on topical minoxidil for hair loss: a survey-based study from the University of Michigan Alopecia Clinic.患者对米诺地尔治疗脱发的看法:密歇根大学脱发诊所的一项基于调查的研究。
Arch Dermatol Res. 2024 Feb 24;316(3):92. doi: 10.1007/s00403-024-02820-9.
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Antioxidants (Basel). 2023 Jun 23;12(7):1332. doi: 10.3390/antiox12071332.
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