Taqi Syed Ahmed, Sami Syed Abdus, Sami Lateef Begum, Zaki Syed Ahmed
Department of Oral and Maxillofacial Sciences, Division of Oral Pathology, Najran University College of Dentistry, Najran, Saudi Arabia.
Department of Forensic Medicine, MGM Medical College and Hospital, Aurangabad, Maharashtra, India.
J Oral Maxillofac Pathol. 2018 May-Aug;22(2):279. doi: 10.4103/jomfp.JOMFP_125_15.
Histopathological examination is considered as gold standard procedure for arriving at a final diagnosis of various lesions of the human body. However, it is limited by a number of alterations of normal morphologic and cytological features that occur as a result of presence of artifacts. These artifacts may occur during surgical removal, fixation, tissue processing, embedding and microtomy and staining and mounting procedures. They can even lead to complete uselessness of the tissue. It is therefore essential to identify the commonly occurring artifacts during histopathological interpretations of tissue sections. This article reviews the common artifacts encountered during slide examination alongside the remedial measures which can be undertaken to differentiate between an artifact and tissue constituent.
组织病理学检查被认为是对人体各种病变做出最终诊断的金标准程序。然而，它受到一些因人为假象的存在而导致的正常形态学和细胞学特征改变的限制。这些人为假象可能出现在手术切除、固定、组织处理、包埋、切片以及染色和封片过程中。它们甚至可能导致组织完全无用。因此，在对组织切片进行组织病理学解读时，识别常见的人为假象至关重要。本文回顾了在玻片检查过程中遇到的常见人为假象以及为区分人为假象和组织成分可采取的补救措施。
