Ahsan Erna, Gautam Saurabh Kumar, Singh Ashok, Kumar Arvind, Phulware Ravi Hari
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Cytojournal. 2025 Apr 9;22:42. doi: 10.25259/Cytojournal_226_2024. eCollection 2025.
The mainstay of treatment for ovarian cancer is surgery. To prevent under-treatment and overtreatment and to choose the best surgical strategy for patients with ovarian tumors, intraoperative pathological assessment is essential. Frozen sections (FSs) have been historically used for intraoperative evaluation. In 1927, cytology was introduced by Dudgeon and Patrick as a new method of intraoperative pathological examination. Diagnosis can be made in minutes by making smears from the lesion, staining them quickly, and analyzing them under a microscope. Following a comprehensive search of the literature, using pertinent keywords in PubMed, and reviewing the data, it was discovered that intraoperative cytology (IOC) had been reported to have a diagnostic accuracy in ovarian lesions comparable to that of FSs. Few of the studies have confirmed that IOC has several benefits over FSs. There are drawbacks as well, which one should be mindful of. In this review, every aspect that is connected to IOC is covered in detail, along with the potential for raising the standard of IOC to make it more applicable in the present times.
卵巢癌治疗的主要手段是手术。为防止治疗不足和过度治疗，并为卵巢肿瘤患者选择最佳手术策略，术中病理评估至关重要。冰冻切片（FS）一直以来都用于术中评估。1927年，达金和帕特里克引入了细胞学作为术中病理检查的新方法。通过从病变部位涂片、快速染色并在显微镜下分析，几分钟内即可做出诊断。在通过在PubMed中使用相关关键词对文献进行全面检索并审查数据后，发现据报道术中细胞学检查（IOC）在卵巢病变中的诊断准确性与FS相当。很少有研究证实IOC比FS有多个优势。当然也存在缺点，对此应予以注意。在本综述中，详细涵盖了与IOC相关的各个方面，以及提高IOC标准使其在当今更适用的可能性。
