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1
Highly infectious plasmids carrying poliovirus cDNA are capable of replication in transfected simian cells.携带脊髓灰质炎病毒互补脱氧核糖核酸的高传染性质粒能够在转染的猿猴细胞中复制。
J Virol. 1986 Aug;59(2):490-3. doi: 10.1128/JVI.59.2.490-493.1986.
2
Expression of the poliovirus genome from infectious cDNA is dependent upon arrangements of eukaryotic and prokaryotic sequences in recombinant plasmids.从感染性互补DNA表达脊髓灰质炎病毒基因组取决于重组质粒中真核和原核序列的排列。
Virology. 1987 Apr;157(2):560-4. doi: 10.1016/0042-6822(87)90302-3.
3
Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals.通过SV40转录和复制信号，从克隆的cDNA产生感染性脊髓灰质炎病毒的效率显著提高。
Nucleic Acids Res. 1984 Jun 25;12(12):5123-41. doi: 10.1093/nar/12.12.5123.
4
Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants.具有转化能力的复制缺陷型猿猴病毒40大T抗原突变体的遗传与生化分析
J Virol. 1985 Jan;53(1):120-7. doi: 10.1128/JVI.53.1.120-127.1985.
5
New host cell system for regulated simian virus 40 DNA replication.用于调控猿猴病毒40 DNA复制的新型宿主细胞系统。
Mol Cell Biol. 1985 Nov;5(11):3231-40. doi: 10.1128/mcb.5.11.3231-3240.1985.
6
Amplification of a bovine papillomavirus-simian virus 40 chimera.
J Virol. 1985 Nov;56(2):625-7. doi: 10.1128/JVI.56.2.625-627.1985.
7
Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase.用纯化的T7 RNA聚合酶合成传染性脊髓灰质炎病毒RNA
Proc Natl Acad Sci U S A. 1986 Apr;83(8):2330-4. doi: 10.1073/pnas.83.8.2330.
8
Activation of the SV40 late promoter: direct effects of T antigen in the absence of viral DNA replication.SV40晚期启动子的激活：在无病毒DNA复制情况下T抗原的直接作用
Cell. 1984 Feb;36(2):381-9. doi: 10.1016/0092-8674(84)90231-9.
9
An infectious cDNA clone of the poliovirus Sabin strain could be used as a stable repository and inoculum for the oral polio live vaccine.脊髓灰质炎病毒萨宾株的感染性 cDNA 克隆可作为口服脊髓灰质炎减毒活疫苗的稳定储存库和接种物。
Virology. 1986 May;151(1):21-30. doi: 10.1016/0042-6822(86)90100-5.
10
Simian virus 40 T antigen is required for viral excision from chromosomes.猴病毒40 T抗原是病毒从染色体上切除所必需的。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7534-8. doi: 10.1073/pnas.81.23.7534.

引用本文的文献

1
Enterovirus A71 DNA-Launched Infectious Clone as a Robust Reverse Genetic Tool.肠道病毒A71 DNA启动的感染性克隆作为一种强大的反向遗传工具。
PLoS One. 2016 Sep 12;11(9):e0162771. doi: 10.1371/journal.pone.0162771. eCollection 2016.
2
Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis.人源1型脊髓灰质炎减毒活疫苗病毒的进化：从疫苗相关麻痹型脊髓灰质炎患者中分离出的毒株特征分析
J Virol. 1997 Oct;71(10):7758-68. doi: 10.1128/JVI.71.10.7758-7768.1997.
3
Classical swine fever virus: recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles.经典猪瘟病毒：从cDNA构建体中恢复感染性病毒并产生重组细胞病变性缺陷干扰颗粒。
J Virol. 1996 Mar;70(3):1588-95. doi: 10.1128/JVI.70.3.1588-1595.1996.
4
Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.基于辛德毕斯病毒DNA的表达载体：体外和体内基因转移的效用。
J Virol. 1996 Jan;70(1):508-19. doi: 10.1128/JVI.70.1.508-519.1996.
5
Molecular characterization of mouse-virulent poliovirus type 1 Mahoney mutants: involvement of residues of polypeptides VP1 and VP2 located on the inner surface of the capsid protein shell.小鼠致病性1型脊髓灰质炎病毒马奥尼突变株的分子特征：衣壳蛋白壳内表面上的VP1和VP2多肽残基的作用
J Virol. 1993 Jul;67(7):3808-17. doi: 10.1128/JVI.67.7.3808-3817.1993.
6
Substitutions in the capsids of poliovirus mutants selected in human neuroblastoma cells confer on the Mahoney type 1 strain a phenotype neurovirulent in mice.在人神经母细胞瘤细胞中筛选出的脊髓灰质炎病毒突变体衣壳中的替换，赋予了马奥尼1型毒株在小鼠中具有神经毒力的表型。
J Virol. 1994 Dec;68(12):8386-91. doi: 10.1128/JVI.68.12.8386-8391.1994.
7
Foot-and-mouth disease virus Lb proteinase can stimulate rhinovirus and enterovirus IRES-driven translation and cleave several proteins of cellular and viral origin.口蹄疫病毒Lb蛋白酶可刺激鼻病毒和肠道病毒内部核糖体进入位点（IRES）驱动的翻译，并切割多种细胞和病毒来源的蛋白质。
J Virol. 1995 Jun;69(6):3465-74. doi: 10.1128/JVI.69.6.3465-3474.1995.
8
Mapping of mutations contributing to the temperature sensitivity of the Sabin 1 vaccine strain of poliovirus.脊髓灰质炎病毒Sabin 1疫苗株温度敏感性相关突变的定位
J Virol. 1995 Sep;69(9):5278-86. doi: 10.1128/JVI.69.9.5278-5286.1995.
9
Engineering a poliovirus type 2 antigenic site on a type 1 capsid results in a chimaeric virus which is neurovirulent for mice.在1型衣壳上构建2型脊髓灰质炎病毒抗原位点会产生一种对小鼠具有神经毒性的嵌合病毒。
EMBO J. 1988 Sep;7(9):2839-47. doi: 10.1002/j.1460-2075.1988.tb03140.x.

本文引用的文献

1
Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals.通过SV40转录和复制信号，从克隆的cDNA产生感染性脊髓灰质炎病毒的效率显著提高。
Nucleic Acids Res. 1984 Jun 25;12(12):5123-41. doi: 10.1093/nar/12.12.5123.
2
Mapping of the late promoter of simian virus 40.猿猴病毒40晚期启动子的定位
Proc Natl Acad Sci U S A. 1984 Jan;81(1):23-7. doi: 10.1073/pnas.81.1.23.
3
Rearrangement and mutagenesis of a shuttle vector plasmid after passage in mammalian cells.穿梭载体质粒在哺乳动物细胞中传代后的重排与诱变
Proc Natl Acad Sci U S A. 1983 May;80(10):3010-4. doi: 10.1073/pnas.80.10.3010.
4
Evidence for the direct involvement of DNA replication origin in synthesis of late SV40 RNA.DNA复制起点直接参与猿猴病毒40型晚期RNA合成的证据。
Nature. 1982 Dec 9;300(5892):500-5. doi: 10.1038/300500a0.
5
Territorial limits and functional anatomy of the simian virus 40 replication origin.猿猴病毒40复制起点的区域界限和功能解剖结构。
Proc Natl Acad Sci U S A. 1982 Jan;79(2):381-5. doi: 10.1073/pnas.79.2.381.
6
Cloned poliovirus complementary DNA is infectious in mammalian cells.克隆的脊髓灰质炎病毒互补DNA在哺乳动物细胞中具有感染性。
Science. 1981 Nov 20;214(4523):916-9. doi: 10.1126/science.6272391.
7
SV40-transformed simian cells support the replication of early SV40 mutants.猴空泡病毒 40（SV40）转化的猿猴细胞支持早期 SV40 突变体的复制。
Cell. 1981 Jan;23(1):175-82. doi: 10.1016/0092-8674(81)90282-8.
8
In vivo sequence requirements of the SV40 early promotor region.猴空泡病毒40早期启动子区域的体内序列要求
Nature. 1981 Mar 26;290(5804):304-10. doi: 10.1038/290304a0.
9
Transfected DNA is mutated in monkey, mouse, and human cells.转染的DNA在猴、小鼠和人类细胞中发生了突变。
Mol Cell Biol. 1984 Oct;4(10):1951-60. doi: 10.1128/mcb.4.10.1951-1960.1984.
10
The simian virus 40 minimal origin and the 72-base-pair repeat are required simultaneously for efficient induction of late gene expression with large tumor antigen.猿猴病毒40最小起始区和72碱基对重复序列同时存在时，才能通过大肿瘤抗原有效诱导晚期基因表达。
Proc Natl Acad Sci U S A. 1984 Oct;81(20):6335-9. doi: 10.1073/pnas.81.20.6335.

携带脊髓灰质炎病毒互补脱氧核糖核酸的高传染性质粒能够在转染的猿猴细胞中复制。

Highly infectious plasmids carrying poliovirus cDNA are capable of replication in transfected simian cells.

作者信息

Kean K M, Wychowski C, Kopecka H, Girard M

出版信息

J Virol. 1986 Aug;59(2):490-3. doi: 10.1128/JVI.59.2.490-493.1986.

DOI:10.1128/JVI.59.2.490-493.1986
PMID:3016309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC253101/
Abstract

We examined events leading to production of infectious poliovirus upon transfection of simian cells with plasmids carrying poliovirus cDNA and simian virus 40 transcription and replication signals. The nature of the simian virus 40 promoter upstream from the poliovirus cDNA had no influence on its infectivity. A high specific infectivity was correlated with plasmid replication, dependent on expression of T antigen either encoded by the plasmid or present in host cells (COS-1).

摘要

我们研究了用携带脊髓灰质炎病毒cDNA以及猿猴病毒40转录和复制信号的质粒转染猴细胞后导致产生传染性脊髓灰质炎病毒的一系列事件。脊髓灰质炎病毒cDNA上游的猿猴病毒40启动子的性质对其感染性没有影响。高特异性感染性与质粒复制相关，这取决于由质粒编码或存在于宿主细胞（COS-1）中的T抗原的表达。