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Opsonin-free, real-time imaging of Cryptococcus neoformans capsule during budding.

作者信息

Paes Hugo Costa, Frazão Stefânia de Oliveira, Rosa Camila Pereira, Albuquerque Patrícia, Casadevall Arturo, Felipe Maria Sueli Soares, Nicola André Moraes

机构信息

a Faculty of Medicine , University of Brasília , Brasília , Brazil.

b Graduate Programme in Microbial Biology, Institute of Biological Sciences, University of Brasília , Brasília , Brazil.

出版信息

Virulence. 2018;9(1):1483-1488. doi: 10.1080/21505594.2018.1515610.

DOI:10.1080/21505594.2018.1515610
PMID:30165795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6177245/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/1d3dd754bf23/kvir-09-01-1515610-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/537eedf5cc89/kvir-09-01-1515610-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/1bbd2d88557c/kvir-09-01-1515610-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/f8f3d3b8a6a9/kvir-09-01-1515610-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/1d3dd754bf23/kvir-09-01-1515610-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/537eedf5cc89/kvir-09-01-1515610-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/1bbd2d88557c/kvir-09-01-1515610-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/f8f3d3b8a6a9/kvir-09-01-1515610-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6173/6177245/1d3dd754bf23/kvir-09-01-1515610-g004.jpg

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本文引用的文献

1
Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection.新型隐球菌的细胞内增殖及荚膜大小决定了巨噬细胞对感染的早期控制。
Sci Rep. 2016 Feb 18;6:21489. doi: 10.1038/srep21489.
2
The Cryptococcus neoformans alkaline response pathway: identification of a novel rim pathway activator.新型隐球菌碱性反应途径：一种新型边缘途径激活剂的鉴定。
PLoS Genet. 2015 Apr 10;11(4):e1005159. doi: 10.1371/journal.pgen.1005159. eCollection 2015 Apr.
3
Capsule growth in Cryptococcus neoformans is coordinated with cell cycle progression.
新型隐球菌的荚膜生长与细胞周期进程相互协调。
mBio. 2014 Jun 17;5(3):e00945-14. doi: 10.1128/mBio.00945-14.
4
Temporal behavior of capsule enlargement by Cryptococcus neoformans.新型隐球菌导致荚膜增大的时间行为。
Eukaryot Cell. 2013 Oct;12(10):1383-8. doi: 10.1128/EC.00163-13. Epub 2013 Aug 16.
5
Antibody binding to Cryptococcus neoformans impairs budding by altering capsular mechanical properties.抗体与新型隐球菌的结合通过改变荚膜的机械性能来阻碍出芽。
J Immunol. 2013 Jan 1;190(1):317-23. doi: 10.4049/jimmunol.1202324. Epub 2012 Dec 10.
6
Fungal cell gigantism during mammalian infection.哺乳动物感染期间真菌细胞的巨细胞化。
PLoS Pathog. 2010 Jun 17;6(6):e1000945. doi: 10.1371/journal.ppat.1000945.
7
Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism.Ab 结合改变新型隐球菌中的基因表达，并直接调节真菌代谢。
J Clin Invest. 2010 Apr;120(4):1355-61. doi: 10.1172/JCI38322. Epub 2010 Mar 24.
8
Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules.新型隐球菌的荚膜通过多糖分子的增大而生长。
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1228-33. doi: 10.1073/pnas.0808995106. Epub 2009 Jan 21.
9
Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival.新型隐球菌中的荚膜增大赋予了对氧化应激的抗性，这提示了一种细胞内存活的机制。
Cell Microbiol. 2008 Oct;10(10):2043-57. doi: 10.1111/j.1462-5822.2008.01186.x. Epub 2008 Jun 28.
10
The polysaccharide capsule of the pathogenic fungus Cryptococcus neoformans enlarges by distal growth and is rearranged during budding.致病真菌新型隐球菌的多糖荚膜通过远端生长而增大，并在出芽过程中重新排列。
Mol Microbiol. 2006 Jan;59(1):67-83. doi: 10.1111/j.1365-2958.2005.04928.x.