依托考昔诱发的中毒性表皮坏死松解症：一例死亡病例报告。
Etoricoxib-induced toxic epidermal necrolysis: A fatal case report.
作者信息
Roy Sukalyan Saha, Mukherjee Shatavisa, Era Nikhil, Mukherjee Mala
机构信息
Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal, India.
Department of Pathology, MGM Medical College, Kishanganj, Bihar, India.
出版信息
Indian J Pharmacol. 2018 May-Jun;50(3):139-142. doi: 10.4103/ijp.IJP_39_17.
Cyclooxygenase inhibitors were developed in the quest of enhanced analgesic efficacy devoid of gastric side effects. High usage of etoricoxib by prescription as well as self-administered routes has led to increasing reports of side effects and adverse reactions including dermatologic reactions in 0.1%-0.3% of cases. The present report enumerates a case of toxic epidermal necrolysis induced by etoricoxib.
环氧化酶抑制剂的研发旨在提高镇痛效果且无胃部副作用。依托考昔通过处方以及自我给药途径的高使用率导致副作用和不良反应的报告不断增加，其中包括0.1%-0.3%的病例出现皮肤反应。本报告列举了一例由依托考昔引起的中毒性表皮坏死松解症病例。
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