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汉堡帕金森日诊所:门诊和住院治疗边界处的一种新治疗理念。

The Hamburg Parkinson day-clinic: a new treatment concept at the border of in- and outpatient care.

机构信息

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Department of Neurology, Charité Berlin, Charitéplatz 1, 10117, Berlin, Germany.

出版信息

J Neural Transm (Vienna). 2018 Oct;125(10):1461-1472. doi: 10.1007/s00702-018-1918-9. Epub 2018 Aug 22.

Abstract

To close a gap between inpatient and outpatient care, the Hamburg Parkinson day-clinic (HPDC) has been developed as a new and comprehensive, individual, interdisciplinary type of treatment for patients with complex Parkinsonian syndromes (PS). First, we describe the HPDC concept, in which a multi-professional medical team of PD specialists provide a time- and personnel-wise intensive care and focuses on the patients' individual deficits and resources. Second, we present short-term outcome results of the first 184 PS patients enrolled during 16 months including objective clinical motor and non-motor scores taken before and after participation in the HPDC, as well as the patients' subjective evaluation of the HPDC. Out of the 184 patients with PS (aged 39-88 years with Hoehn and Yahr scores between 1.0 and 4.5), 169 were diagnosed to have Parkinson disease (PD). HPDC treatment led to improvement of all applied motor (UPDRS III, AIMS) and non-motor (BDI-II, MoCA, PDNMS, PDSS-2, King's PD Pain Scale, QUIP, PDQ-39) scores (p < 0.05) indicating benefits for akinesia, tremor, dyskinesia, cognition, sleep, pain, impulse control disorders and quality of life. Patients evaluated HPDC care positively with values from 1.39 to 2.79 ("very good" to "satisfying") with an overall grade of 1.69 ("good") on a 6-point Likert scale (1-6: best to worst). Patients with advanced PS benefit from the HPDC concept which is considered to close a gap between inpatient and outpatient care.

摘要

为了弥合住院和门诊护理之间的差距,汉堡帕金森日间诊所(HPDC)已发展成为一种新的、全面的、个体化的、跨学科的治疗复杂帕金森综合征(PS)患者的方法。首先,我们描述了 HPDC 概念,其中一个多专业的 PD 专家医疗团队提供了密集的时间和人员护理,并专注于患者的个体缺陷和资源。其次,我们介绍了在 16 个月内参与的前 184 名 PS 患者的短期结果,包括参与 HPDC 前后的客观临床运动和非运动评分,以及患者对 HPDC 的主观评价。在 184 名 PS 患者(年龄 39-88 岁,Hoehn 和 Yahr 评分 1.0-4.5)中,169 名被诊断为帕金森病(PD)。HPDC 治疗导致所有应用运动(UPDRS III、AIMS)和非运动(BDI-II、MoCA、PDNMS、PDSS-2、King's PD 疼痛量表、QUIP、PDQ-39)评分的改善(p<0.05),表明对运动迟缓、震颤、运动障碍、认知、睡眠、疼痛、冲动控制障碍和生活质量有益。患者对 HPDC 护理的评价非常积极,分值在 1.39 到 2.79 之间(“非常好”到“满意”),总体等级为 1.69(“好”),采用 6 分李克特量表(1-6:最好到最差)。晚期 PS 患者受益于 HPDC 概念,该概念被认为可以弥合住院和门诊护理之间的差距。

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