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意大利污水中人杯状病毒的发生和遗传多样性。

Occurrence and Genetic Diversity of Human Cosavirus in Sewage in Italy.

机构信息

Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.

Department Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.

出版信息

Food Environ Virol. 2018 Dec;10(4):386-390. doi: 10.1007/s12560-018-9356-2. Epub 2018 Aug 30.

Abstract

Human Cosavirus (HCoSV) is a newly discovered virus whose role in human enteric diseases is still unknown. In Italy, the prevalence and genetic diversity of HCoSV are unexplored. One hundred forty-one raw sewage samples collected throughout Italy were screened for HCoSV by RT-nested PCR. HCoSV was detected in 25.5% of samples. Species A, C, and D, and a potentially new species were detected. Our results show a significant circulation and heterogeneity of HCoSV in Italy.

摘要

人冠状病毒(HCoSV)是一种新发现的病毒,其在人类肠道疾病中的作用尚不清楚。在意大利,HCoSV 的流行率和遗传多样性尚不清楚。通过 RT-巢式 PCR 法对意大利各地采集的 141 份原始污水样本进行 HCoSV 筛查。在 25.5%的样本中检测到 HCoSV。检测到了 A、C 和 D 种以及一种可能的新种。我们的研究结果表明,HCoSV 在意大利具有显著的传播和异质性。

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