Menage Lucy, Yodmeeklin Arpaporn, Khamrin Pattara, Kumthip Kattareeya, Maneekarn Niwat
Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Infect Genet Evol. 2017 Sep;53:1-6. doi: 10.1016/j.meegid.2017.05.005. Epub 2017 May 8.
Human cosavirus and saffold virus are both newly discovered members of the Picornaviridae family. It has been suggested that these viruses may be the causative agents of acute gastroenteritis. In this study, 1093 stool samples collected from patients with acute gastroenteritis between January 2014 and December 2016, were screened for cosavirus and saffold virus using reverse transcription-polymerase chain reaction. The viral genotypes were then established via nucleotide sequencing. Here, cosavirus was detected in 16 of 1093 stool samples (1.5%) and saffold virus was detected in 18 of 1093 stool samples (1.6%). The saffold virus genotypes 1 (16.7%), 2 (50%) and 6 (33.3%), and the cosavirus genetic groups A (87.5%), C (6.25%) and D (6.25%), were all identified across the three-year study period. Interestingly, saffold virus genotype 6 has now been detected for the first time in Thailand. The present study provides the prevalence of cosavirus and saffold virus with the emergence of saffold virus genotype 6 in Thailand.
人科萨病毒和萨福尔德病毒都是新发现的小RNA病毒科成员。有人认为这些病毒可能是急性胃肠炎的病原体。在本研究中，使用逆转录-聚合酶链反应对2014年1月至2016年12月期间从急性胃肠炎患者中收集的1093份粪便样本进行了科萨病毒和萨福尔德病毒筛查。然后通过核苷酸测序确定病毒基因型。在此，在1093份粪便样本中的16份（1.5%）中检测到科萨病毒，在1093份粪便样本中的18份（1.6%）中检测到萨福尔德病毒。在三年的研究期间，共鉴定出萨福尔德病毒基因型1（16.7%）、2（50%）和6（33.3%），以及科萨病毒遗传组A（87.5%）、C（6.25%）和D（6.25%）。有趣的是，萨福尔德病毒基因型6首次在泰国被检测到。本研究提供了泰国科萨病毒和萨福尔德病毒的流行情况以及萨福尔德病毒基因型6的出现情况。
