Hartman G E, Smolik L M, Shochat S J
Am J Dis Child. 1986 Sep;140(9):925-8. doi: 10.1001/archpedi.1986.02140230095042.
Multicystic dysplastic kidney is the most frequent cause of an abdominal mass in the neonate, but controversy continues as to the optimal management of these lesions, since little is known about their natural history. Experience with two complicated cases and a review of reports of retained multicystic dysplastic kidneys suggest that such lesions pose a significant risk to their hosts. Malignancy, reversible hypertension, pain, and mass effect have been associated with retained lesions. Infection is another potential hazard that is frequently cited but poorly documented in the literature. In light of the currently low morbidity and mortality associated with operation and anesthesia in the neonatal period, resection appears to be the treatment of choice for the neonate with a multicystic dysplastic kidney.
多囊性发育不良肾是新生儿腹部肿块最常见的原因，但对于这些病变的最佳治疗方法仍存在争议，因为对其自然病程了解甚少。两例复杂病例的经验以及对保留的多囊性发育不良肾报告的回顾表明，此类病变对其宿主构成重大风险。恶性肿瘤、可逆性高血压、疼痛和占位效应与保留的病变有关。感染是另一个经常被提及但文献记载较少的潜在危害。鉴于目前新生儿期手术和麻醉的发病率和死亡率较低，对于患有多囊性发育不良肾的新生儿，切除似乎是首选的治疗方法。
