School of Chemistry, Alborz Campus, University of Tehran, Tehran, Iran.
Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran.
Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 5;206:430-436. doi: 10.1016/j.saa.2018.08.026. Epub 2018 Aug 16.
A luminescence nanosensor has been developed for analysis of Ornidazole in biological samples using graphene-quantum-dot-embedded silica molecular imprinted polymer (GQD-SMIP) as a selective probe for this analyte. The GQD-SMIP was found to possess a strong fluorescent emission at 450 nm upon excitation at 365 nm. This emission was found to linearly quench in the presence of Ornidazole in a concentration range of 0.75 to 30 μM. A detection limit of 0.24 μM was reached using the probe and the sensor was successfully used in the determination of the analyte in plasma samples.
一种基于石墨烯量子点嵌入硅基分子印迹聚合物（GQD-SMIP）的荧光纳米传感器被开发出来，用于分析生物样品中的奥硝唑。研究发现，GQD-SMIP 在 365nm 激发下，于 450nm 处具有强烈的荧光发射。当存在奥硝唑时，该发射会在 0.75 至 30µM 的浓度范围内线性猝灭。使用该探针可达到 0.24µM 的检测限，并且该传感器成功地用于测定血浆样品中的分析物。
