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与膝关节中碱性磷酸钙和二水焦磷酸钙晶体沉积相关的影像学异常模式。

Patterns of radiographic abnormalities associated with basic calcium phosphate and calcium pyrophosphate dihydrate crystal deposition in the knee.

作者信息

Halverson P B, McCarty D J

出版信息

Ann Rheum Dis. 1986 Jul;45(7):603-5. doi: 10.1136/ard.45.7.603.

DOI:10.1136/ard.45.7.603
PMID:3017246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001944/
Abstract

Radiographs and synovial fluids from 66 knees representing 59 patients with symptomatic osteoarthritis were evaluated to determine the pattern of radiographic abnormalities associated with basic calcium phosphate (BCP), calcium pyrophosphate dihydrate (CPPD), or both crystals together. Crystals were found in 71% of fluids. In general, CPPD crystals correlated with patient age, while BCP crystals correlated with joint degeneration. Synovial fluid BCP and CPPD crystals were found together more often than either alone. Joint compartment narrowing and osteophytes in three compartments are often associated with BCP crystals.

摘要

对代表59例有症状骨关节炎患者的66个膝关节的X光片和滑液进行评估,以确定与碱性磷酸钙(BCP)、二水焦磷酸钙(CPPD)或两种晶体同时存在相关的X光异常模式。71%的滑液中发现了晶体。一般来说,CPPD晶体与患者年龄相关,而BCP晶体与关节退变相关。滑液中BCP和CPPD晶体同时出现的情况比单独出现更为常见。三个关节腔的关节间隙变窄和骨赘常与BCP晶体相关。

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Ann Rheum Dis. 1986 Jul;45(7):603-5. doi: 10.1136/ard.45.7.603.
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本文引用的文献

1
Erosive arthritis associated with apatite crystal deposition.与磷灰石晶体沉积相关的侵蚀性关节炎。
Arthritis Rheum. 1981 Jan;24(1):31-7. doi: 10.1002/art.1780240105.
2
Apatite associated destructive arthritis.磷灰石相关性破坏性关节炎
Br J Rheumatol. 1984 May;23(2):84-91. doi: 10.1093/rheumatology/23.2.84.
3
Milwaukee Shoulder syndrome: eleven additional cases with involvement of the knee in seven (basic calcium phosphate crystal deposition disease).密尔沃基肩综合征:另外11例,其中7例累及膝关节(碱性磷酸钙晶体沉积病)
Semin Arthritis Rheum. 1984 Aug;14(1):36-44. doi: 10.1016/0049-0172(84)90007-6.
4
Release of collagenase, neutral protease, and prostaglandins from cultured mammalian synovial cells by hydroxyapatite and calcium pyrophosphate dihydrate crystals.羟基磷灰石和二水焦磷酸钙晶体从培养的哺乳动物滑膜细胞中释放胶原酶、中性蛋白酶和前列腺素。
Arthritis Rheum. 1981 Nov;24(11):1338-44. doi: 10.1002/art.1780241102.
5
Alizarin red S staining as a screening test to detect calcium compounds in synovial fluid.茜素红S染色作为一种筛查试验,用于检测滑液中的钙化合物。
Arthritis Rheum. 1983 Feb;26(2):191-200. doi: 10.1002/art.1780260211.
6
Synovial fluid crystals in osteoarthritis.骨关节炎中的滑液晶体
Arthritis Rheum. 1985 May;28(5):511-5. doi: 10.1002/art.1780280507.
7
Mixed crystal deposition in an osteoarthritic joint.骨关节炎关节中的混合晶体沉积。
J Pathol. 1977 Sep;123(1):1-4. doi: 10.1002/path.1711230102.
8
Synovial fluid crystals.滑液晶体
Q J Med. 1979 Oct;48(192):533-53.
9
Mixed crystal deposition disease and osteoarthritis.混合性晶体沉积病与骨关节炎。
Br Med J. 1978 Jan 21;1(6106):150. doi: 10.1136/bmj.1.6106.150.
10
Arthritis associated with apatite crystals.与磷灰石晶体相关的关节炎
Ann Intern Med. 1977 Oct;87(4):411-6. doi: 10.7326/0003-4819-87-4-411.