Lee Mokhyeon, Park Jiyoung, Choi Hojung, Lee Haebeom, Jeong Seong Mok
Department of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
Department of Veterinary Diagnostic Imaging, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.
J Vet Sci. 2018 Nov 30;19(6):827-834. doi: 10.4142/jvs.2018.19.6.827.
The purpose of this study was to evaluate the clinical and imaging characteristics of canine splenic tumors and to establish guidelines for the presurgical assessment of splenic tumors in dogs. Fifty-seven dogs that underwent total splenectomy for the treatment of splenic tumors were evaluated by examining medical records, hematologic results, diagnostic imaging results, and histopathologic results. The maximum lesion size from ultrasonography was significantly different between malignant and benign tumors ( = 0.002). There was a correlation between tumor margination and type of splenic tumors ( = 0.045). Precontrast lesion attenuation on computed tomography was significantly different between splenic malignant and benign tumors ( = 0.001). The mean ± SD precontrast lesion attenuation of malignant tumors was 40.3 ± 5.9 Hounsfield units (HU), and for benign tumors, it was 52.8 ± 6.8 HU. In conclusion, some variables of the imaging examination could be used to distinguish the type of splenic tumor. Based on the study results, using a diagnostic flowchart would be effective in increasing the survival rate of patients with splenic malignant tumors. In addition, fine needle aspiration or magnetic resonance imaging prior to surgical exploration and histopathologic examination may be useful in achieving a more accurate diagnosis.
本研究的目的是评估犬脾脏肿瘤的临床和影像学特征，并制定犬脾脏肿瘤术前评估的指导原则。通过检查病历、血液学结果、诊断性影像学结果和组织病理学结果，对57只因治疗脾脏肿瘤而接受全脾切除术的犬进行了评估。超声检查中恶性肿瘤和良性肿瘤的最大病变大小存在显著差异（P = 0.002）。肿瘤边界与脾脏肿瘤类型之间存在相关性（P = 0.045）。计算机断层扫描上的平扫病变衰减在脾脏恶性肿瘤和良性肿瘤之间存在显著差异（P = 0.001）。恶性肿瘤的平扫病变平均衰减值±标准差为40.3±5.9亨氏单位（HU），良性肿瘤为52.8±6.8 HU。总之，影像学检查的一些变量可用于区分脾脏肿瘤的类型。根据研究结果，使用诊断流程图将有效地提高脾脏恶性肿瘤患者的生存率。此外，在手术探查和组织病理学检查之前进行细针穿刺或磁共振成像可能有助于实现更准确的诊断。
