前额叶皮层中氧合血红蛋白对认知任务的反应：一项系统综述。
Oxyhemoglobin changes in the prefrontal cortex in response to cognitive tasks: a systematic review.
作者信息
Bonetti Leandro Viçosa, Hassan Syed A, Lau Sin-Tung, Melo Luana T, Tanaka Takako, Patterson Kara K, Reid W Darlene
机构信息
a Department of Physical Therapy , University of Toronto , Toronto, ON , Canada.
b Department of Physical Therapy , Universidade de Caxias do Sul , Rio Grande do Sul , Brazil.
出版信息
Int J Neurosci. 2019 Feb;129(2):195-203. doi: 10.1080/00207454.2018.1518906. Epub 2018 Oct 31.
PURPOSE OF THE STUDY
the aim of this study was to synthesize PFC fNIRS outcomes on the effects of cognitive tasks compared to resting/baseline tasks in healthy adults from studies utilizing a pre/post design.
MATERIAL AND METHODS
original research studies were searched from seven databases (MEDLINE, EMBASE, CENTRAL, CINAHL, SCOPUS, PEDro and PubMed). Subsequently, two independent reviewers screened the titles and abstracts followed by full-text reviews to assess the studies' eligibility.
RESULTS
eleven studies met the inclusion criteria and had data abstracted and quality assessed. Methodology varied considerably and yet cognitive tasks resulted in the ΔOHb increasing in 8 of the 11 and ΔHHb decreasing in 8 of 8 studies that reported this outcome. The cognitive tasks from 10 of the 11 studies were classified as "Working Memory" and "Verbal Fluency Tasks".
CONCLUSIONS
although, the data comparison was challenging provided the heterogeneity in methodology, the results across studies were similar.
研究目的
本研究旨在综合利用前后设计的研究中，健康成年人在认知任务与静息/基线任务作用下的全氟碳化物功能近红外光谱（PFC fNIRS）结果。
材料与方法
从七个数据库（MEDLINE、EMBASE、CENTRAL、CINAHL、SCOPUS、PEDro和PubMed）检索原始研究。随后，两名独立评审员先筛选标题和摘要，再进行全文评审以评估研究的合格性。
结果
11项研究符合纳入标准，对其数据进行了提取并评估了质量。方法差异很大，但在报告该结果的11项研究中有8项认知任务导致氧合血红蛋白（ΔOHb）增加，在8项研究中有8项脱氧血红蛋白（ΔHHb）减少。11项研究中的10项认知任务被归类为“工作记忆”和“语言流畅性任务”。
结论
尽管由于方法的异质性，数据比较具有挑战性，但各研究结果相似。
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