Hofmann Patrick, Benden Christian, Kohler Malcolm, Schuurmans Macé M
Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
J Thorac Dis. 2018 Jul;10(7):4609-4618. doi: 10.21037/jtd.2018.07.16.
Smoking remains the leading cause of preventable disease and death in the developed world and kills half of all long-term users. Smoking resumption after heart or lung transplantation is associated with allograft dysfunction, higher incidence of cancer, and reduced overall survival. Although self-reporting is considered an unreliable method for tobacco use detection, implementing systematic cotinine-based screening has proven challenging. This review examines the prevalence of smoking resumption in thoracic transplant patients, explores the risk factors associated with a post-transplant smoking resumption and discusses the currently available smoking cessation interventions for transplant patients.
在发达国家,吸烟仍是可预防疾病和死亡的首要原因,且半数长期吸烟者会因此死亡。心脏或肺移植后复吸与移植物功能障碍、癌症发病率升高及总体生存率降低有关。尽管自我报告被认为是检测烟草使用情况的不可靠方法,但事实证明,实施基于可替宁的系统筛查颇具挑战性。本文综述了胸科移植患者复吸的患病率,探讨了与移植后复吸相关的危险因素,并讨论了目前可供移植患者使用的戒烟干预措施。