Division of Clinical Dentistry, School of Dentistry, International Medical University, 57000 Kuala Lumpur, Malaysia.
School of Medicine and Dentistry, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Drug Discov Today. 2019 Jan;24(1):85-98. doi: 10.1016/j.drudis.2018.08.012. Epub 2018 Aug 31.
Maintenance of oral health is a major challenge in dentistry. Different materials have been used to treat various dental diseases, although treatment success is limited by features of the biomaterials used. To overcome these limitations, materials incorporated with nanoparticles (NPs) can be used in dental applications including endodontics, periodontics, tissue engineering, oral surgery, and imaging. The unique properties of NPs, including their surface:volume ratio, antibacterial action, physical, mechanical, and biological characteristics, and unique particle size have rendered them effective vehicles for dental applications. In this review, we provide insights into the various applications of NPs in dentistry, including their benefits, limitations, properties, actions and future potential.
口腔健康的维护是牙科领域的一大挑战。尽管治疗的成功受到所使用的生物材料特性的限制，但已经有不同的材料被用于治疗各种牙科疾病。为了克服这些限制，可以将纳米颗粒（NPs）与材料结合使用于牙科应用，包括牙髓学、牙周病学、组织工程学、口腔外科学和影像学。NPs 的独特性质，包括其比表面积、抗菌作用、物理、机械和生物学特性以及独特的粒径，使它们成为牙科应用的有效载体。在这篇综述中，我们深入探讨了 NPs 在牙科领域的各种应用，包括它们的优势、局限性、性质、作用和未来潜力。
