Cherinet Fashe Markos, Tekalign Sophia Yoseph, Anbesse Dereje Hayilu, Bizuneh Zewdu Yenegeta
Department of Ophthalmology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
BMC Ophthalmol. 2018 Sep 3;18(1):232. doi: 10.1186/s12886-018-0899-7.
Low vision and blindness are major public health problems. A vast burden of worlds visually impaired live in low-income settings especially in sub Saharan Africa. In such settings the blindness is associated with considerable disability and excess mortality, resulting in huge economic and social consequence. The main purpose of this study was to determine the prevalence and associated factors of low vision and blindness among patients at St. Paul's hospital millenium medical college.
Institution based cross sectional design study was carried out from January to April, 2017 with sample size of 904. Systematic random sampling was used to recruit the study subjects. Retrospective medical chart review was done; data was entered into and analyzed by SPSS 23. Descriptive statistics such as frequency cross tabulation and chi-square test was carried out to translate data into information. P-value less than 0.05 was considered as statistically significant.
A total of 881 subjects with a response rate of 97.4% selected. The mean age of the study subjects was 44.53(SD: ± 21.85) with a range of 1-100 years. The prevalence of low vision and blindness was 91 (10.3% (95% CI: 8.2, 12.3)), and 64 (7.3 95%CI: 5.7, 9.0)) respectively. Age (p-value < 0.001), cataract (p-value = 0.002), glaucoma (p-value = 0.002) and age related macular degeneration (p-value < 0.001) were significantly associated with low vision and blindness.
Low vision and blindness found in this study was high. Age, cataract, glaucoma and age related macular degeneration were significantly associated with low vision and blindness. This amount of magnitude will be reduced if prevention, early diagnosis and management will be targeted towards avoidable causes of visual impairment.
低视力和失明是主要的公共卫生问题。世界上大量视力受损者生活在低收入地区,尤其是撒哈拉以南非洲。在这些地区,失明与相当严重的残疾和过高的死亡率相关,导致巨大的经济和社会后果。本研究的主要目的是确定圣保罗医院千禧医学院患者中低视力和失明的患病率及相关因素。
2017年1月至4月进行了基于机构的横断面设计研究,样本量为904。采用系统随机抽样招募研究对象。进行回顾性病历审查;数据录入SPSS 23并进行分析。进行描述性统计,如频率交叉表和卡方检验,以将数据转化为信息。P值小于0.05被认为具有统计学意义。
共选取881名受试者,应答率为97.4%。研究对象的平均年龄为44.53岁(标准差:±21.85),年龄范围为1至100岁。低视力和失明的患病率分别为91例(10.3%(95%置信区间:8.2,12.3))和64例(7.3%,95%置信区间:5.7,9.0))。年龄(P值<0.001)、白内障(P值=0.002)、青光眼(P值=0.002)和年龄相关性黄斑变性(P值<0.001)与低视力和失明显著相关。
本研究中发现的低视力和失明发生率较高。年龄、白内障、青光眼和年龄相关性黄斑变性与低视力和失明显著相关。如果针对可避免的视力损害原因进行预防、早期诊断和管理,这一程度将会降低。