一种针对淋巴结相关病毒/人嗜T淋巴细胞病毒III型抗体新检测方法的评估。

Evaluation of a new assay for antibodies to LAV/HTLV III.

作者信息

Maskill W, Healey D, Wootten A, Silvester C, Johnson S, O'Dwyer C, Jacklin R, Pringle R, Gust I, Harden P

出版信息

J Virol Methods. 1986 Jul;13(4):273-8. doi: 10.1016/0166-0934(86)90051-0.

Abstract

The sensitivity, specificity and reproducibility of an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to LAV/HTLV III produced by Genetic Systems was assessed with the identical panel of sera used in previous evaluations of anti-HTLV III ELISAs. The results from this study show that the Genetic Systems anti-LAV/HTLV III ELISA proved to be of equivalent sensitivity and to have higher specificity than assays currently used in Australia for screening purposes while maintaining high levels of intra- and inter-laboratory reproducibility.

摘要

使用与先前抗HTLV III酶联免疫吸附测定（ELISA）评估中相同的血清组，对遗传系统公司生产的用于检测抗LAV/HTLV III抗体的ELISA的敏感性、特异性和可重复性进行了评估。这项研究的结果表明，遗传系统公司的抗LAV/HTLV III ELISA被证明具有同等的敏感性，并且与澳大利亚目前用于筛查目的的检测方法相比具有更高的特异性，同时保持了高水平的实验室内和实验室间可重复性。