Hubková Beáta, Rácz Oliver, Bódy Gabriel, Frišman Eugen, Mareková Mária
Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University in Košice, Faculty of Medicine, Košice, Slovakia.
Department of Pathological Physiology, Pavol Jozef Šafárik University in Košice, Faculty of Medicine, Košice, Slovakia.
Interdiscip Toxicol. 2018 May;11(1):22-26. doi: 10.2478/intox-2018-0003. Epub 2018 Aug 6.
Toluene abuse is one of the most common addictions among marginalized Roma. The aim of the study was the comparison of urinary toluene metabolite levels in marginalized population of Eastern Slovakia as compared to the majority population, and to verify the validity of the answers, given in the questionnaires, regarding toluene abuse. The study was carried out as part of the HEPA-META project aiming to map the prevalence of health problems in marginalized Roma. The majority of people living outside the area of the segregated Roma communities comprised the control group. The total number of study participants was 770. Statistically significant differences in the levels of hippuric acid and -cresol were found between Roma and the majority population. Variations in urinary hippuric acid levels in addition to toluene abuse can be caused also by dietary factors, medical treatment as well as alcohol consumption, which is frequent (not only) in marginalized communities.
甲苯滥用是边缘化罗姆人群体中最常见的成瘾问题之一。本研究的目的是比较斯洛伐克东部边缘化人群与多数人群尿中甲苯代谢物水平，并验证问卷中关于甲苯滥用问题答案的有效性。该研究是“HEPA - META”项目的一部分，旨在摸清边缘化罗姆人群体中健康问题的流行情况。居住在隔离罗姆社区以外地区的大多数人构成对照组。研究参与者总数为770人。罗姆人和多数人群在马尿酸和对甲酚水平上存在统计学显著差异。除甲苯滥用外，饮食因素、药物治疗以及饮酒（不仅在边缘化社区常见）也可能导致尿中马尿酸水平变化。
