环磷酰胺对鸡T细胞系统的抑制作用。
Suppressive effect of cyclophosphamide on the T-cell system in chickens.
作者信息
Sharma J M, Lee L F
出版信息
Infect Immun. 1977 Jul;17(1):227-30. doi: 10.1128/iai.17.1.227-230.1977.
Abstract
Neonatal administration of 16 mg of cyclophosphamide in inbred chickens resulted in a transient, but profound, deficiency in the in vitro proliferative response of spleen cells. Functional T-cell deficiency was accompanied by a marked morphological degeneration in the thymus and thymus-dependent areas in the spleen.
摘要
对近交系雏鸡新生期给予16毫克环磷酰胺，导致脾脏细胞体外增殖反应出现短暂但严重的缺陷。功能性T细胞缺陷伴随着胸腺以及脾脏中胸腺依赖区明显的形态学退变。
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